Innovations, challenges, and minimal information for standardization of humanized mice

Mice xenotransplanted with human cells and/or expressing human gene products (also known as “humanized mice”) recapitulate the human evolutionary specialization and diversity of genotypic and phenotypic traits. These models can provide a relevant in vivo context for understanding of human‐specific p...

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Detalles Bibliográficos
Autores principales: Stripecke, Renata, Münz, Christian, Schuringa, Jan Jacob, Bissig, Karl‐Dimiter, Soper, Brian, Meeham, Terrence, Yao, Li‐Chin, Di Santo, James P, Brehm, Michael, Rodriguez, Estefania, Wege, Anja Kathrin, Bonnet, Dominique, Guionaud, Silvia, Howard, Kristina E, Kitchen, Scott, Klein, Florian, Saeb‐Parsy, Kourosh, Sam, Johannes, Sharma, Amar Deep, Trumpp, Andreas, Trusolino, Livio, Bult, Carol, Shultz, Leonard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338801/
https://www.ncbi.nlm.nih.gov/pubmed/32578942
http://dx.doi.org/10.15252/emmm.201708662

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