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Wide variation in tissue, systemic, and drain fluid exposure after oxaliplatin-based HIPEC: results of the GUTOX study

PURPOSE: In this exploratory study, the effect of postprocedural flushing with crystalloids after oxaliplatin-based hyperthermic intraperitoneal chemotherapy (HIPEC) on platinum concentrations in peritoneal tissue, blood, and drain fluid was studied. Interpatient variability in oxaliplatin pharmacok...

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Detalles Bibliográficos
Autores principales:	de Jong, Loek A. W., Elekonawo, Fortuné M. K., Lambert, Marie, de Gooyer, Jan Marie, Verheul, Henk M. W., Burger, David M., de Wilt, Johannes H. W., Chatelut, Etienne, ter Heine, Rob, de Reuver, Philip R., Bremers, Andre J. A., van Erp, Nielka P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338818/ https://www.ncbi.nlm.nih.gov/pubmed/32594200 http://dx.doi.org/10.1007/s00280-020-04107-y

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