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Initial experience with [(18)F]DPA-714 TSPO-PET to image inflammation in primary angiitis of the central nervous system

PURPOSE: Primary angiitis of the central nervous system (PACNS) is a heterogeneous, rare, and poorly understood inflammatory disease. We aimed at non-invasive imaging of activated microglia/macrophages in patients with PACNS by PET-MRI targeting the translocator protein (TSPO) with [(18)F]DPA-714 to...

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Detalles Bibliográficos
Autores principales: Backhaus, Philipp, Roll, Wolfgang, Beuker, Carolin, Zinnhardt, Bastian, Seifert, Robert, Wenning, Christian, Eisenblätter, Michel, Thomas, Christian, Schmidt-Pogoda, Antje, Strunk, Daniel, Wagner, Stefan, Faust, Andreas, Tüttelmann, Frank, Röpke, Albrecht, Jacobs, Andreas H., Stummer, Walter, Wiendl, Heinz, Meuth, Sven G., Schäfers, Michael, Grauer, Oliver, Minnerup, Jens
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338821/
https://www.ncbi.nlm.nih.gov/pubmed/31960097
http://dx.doi.org/10.1007/s00259-019-04662-4

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