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Blood Targets of Adjuvant Drugs Against COVID19

While waiting for the vaccine and/or the best treatment for COVID19, several drugs have been identified as potential adjuvant drugs to counteract the viral action. Several drugs, in fact, have been suggested for their ancillary antiviral role. Viral proteases and peptidases, may interact with well-k...

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Autores principales: Di Micco, Pierpaolo, Di Micco, Gianluca, Russo, Vincenzo, Poggiano, Maria Rita, Salzano, Ciro, Bosevski, Marijan, Imparato, Michele, Fontanella, Luca, Fontanella, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338832/
https://www.ncbi.nlm.nih.gov/pubmed/32694923
http://dx.doi.org/10.2147/JBM.S256121
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author Di Micco, Pierpaolo
Di Micco, Gianluca
Russo, Vincenzo
Poggiano, Maria Rita
Salzano, Ciro
Bosevski, Marijan
Imparato, Michele
Fontanella, Luca
Fontanella, Andrea
author_facet Di Micco, Pierpaolo
Di Micco, Gianluca
Russo, Vincenzo
Poggiano, Maria Rita
Salzano, Ciro
Bosevski, Marijan
Imparato, Michele
Fontanella, Luca
Fontanella, Andrea
author_sort Di Micco, Pierpaolo
collection PubMed
description While waiting for the vaccine and/or the best treatment for COVID19, several drugs have been identified as potential adjuvant drugs to counteract the viral action. Several drugs, in fact, have been suggested for their ancillary antiviral role. Viral proteases and peptidases, may interact with well-known drugs such as anticoagulants, antihypertensives, antiserotoninergics and immunomodulants. We here report a basic list of these drugs that include bioflavonoids, heparinoids, ACE inhibitors, angiotensin receptor blockers, antiserotoninergics, and monoclonal antibodies against cytokines that may interact with the viral cycle.
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spelling pubmed-73388322020-07-20 Blood Targets of Adjuvant Drugs Against COVID19 Di Micco, Pierpaolo Di Micco, Gianluca Russo, Vincenzo Poggiano, Maria Rita Salzano, Ciro Bosevski, Marijan Imparato, Michele Fontanella, Luca Fontanella, Andrea J Blood Med Expert Opinion While waiting for the vaccine and/or the best treatment for COVID19, several drugs have been identified as potential adjuvant drugs to counteract the viral action. Several drugs, in fact, have been suggested for their ancillary antiviral role. Viral proteases and peptidases, may interact with well-known drugs such as anticoagulants, antihypertensives, antiserotoninergics and immunomodulants. We here report a basic list of these drugs that include bioflavonoids, heparinoids, ACE inhibitors, angiotensin receptor blockers, antiserotoninergics, and monoclonal antibodies against cytokines that may interact with the viral cycle. Dove 2020-07-02 /pmc/articles/PMC7338832/ /pubmed/32694923 http://dx.doi.org/10.2147/JBM.S256121 Text en © 2020 Di Micco et al. http://creativecommons.org/licenses/by-nc/3.0/ This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at https://www.dovepress.com/terms.php and incorporate the Creative Commons Attribution – Non Commercial (unported, v3.0) License (http://creativecommons.org/licenses/by-nc/3.0/). By accessing the work you hereby accept the Terms. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed. For permission for commercial use of this work, please see paragraphs 4.2 and 5 of our Terms (https://www.dovepress.com/terms.php).
spellingShingle Expert Opinion
Di Micco, Pierpaolo
Di Micco, Gianluca
Russo, Vincenzo
Poggiano, Maria Rita
Salzano, Ciro
Bosevski, Marijan
Imparato, Michele
Fontanella, Luca
Fontanella, Andrea
Blood Targets of Adjuvant Drugs Against COVID19
title Blood Targets of Adjuvant Drugs Against COVID19
title_full Blood Targets of Adjuvant Drugs Against COVID19
title_fullStr Blood Targets of Adjuvant Drugs Against COVID19
title_full_unstemmed Blood Targets of Adjuvant Drugs Against COVID19
title_short Blood Targets of Adjuvant Drugs Against COVID19
title_sort blood targets of adjuvant drugs against covid19
topic Expert Opinion
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338832/
https://www.ncbi.nlm.nih.gov/pubmed/32694923
http://dx.doi.org/10.2147/JBM.S256121
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