11g, a Potent Antifungal Candidate, Enhances Candida albicans Immunogenicity by Unmasking β-Glucan in Fungal Cell Wall

In the course of optimizing GPI biosynthesis inhibitors, we designed and synthetized a 2-aminonicotinamide derivative named 11g. After evaluating the antifungal activity of compound 11g in vitro, we investigated the influences of 11g on fungi immunogenicity. In addition, we also took advantage of mu...

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Detalles Bibliográficos
Autores principales: Huang, Xin, Liu, Yu, Ni, Tingjunhong, Li, Liping, Yan, Lan, An, Maomao, Zhang, Dazhi, Jiang, Yuanying
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338940/
https://www.ncbi.nlm.nih.gov/pubmed/32695076
http://dx.doi.org/10.3389/fmicb.2020.01324

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338940/
https://www.ncbi.nlm.nih.gov/pubmed/32695076
http://dx.doi.org/10.3389/fmicb.2020.01324

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