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CRISPR-sub: Analysis of DNA substitution mutations caused by CRISPR-Cas9 in human cells
CRISPR-Cas9 induces DNA cleavages at desired target sites in a guide RNA-dependent manner; DNA editing occurs through the resulting activity of DNA repair processes including non-homologous end joining (NHEJ), which is dominant in mammalian cells. NHEJ repair frequently causes small insertions and d...
| Autores principales: | , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Research Network of Computational and Structural Biotechnology
2020
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7338987/ https://www.ncbi.nlm.nih.gov/pubmed/32670508 http://dx.doi.org/10.1016/j.csbj.2020.06.026 |