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Metabolic Fingerprinting Links Oncogenic PIK3CA with Enhanced Arachidonic Acid-Derived Eicosanoids

Oncogenic transformation is associated with profound changes in cellular metabolism, but whether tracking these can improve disease stratification or influence therapy decision-making is largely unknown. Using the iKnife to sample the aerosol of cauterized specimens, we demonstrate a new mode of rea...

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Detalles Bibliográficos
Autores principales:	Koundouros, Nikos, Karali, Evdoxia, Tripp, Aurelien, Valle, Adamo, Inglese, Paolo, Perry, Nicholas J.S., Magee, David J., Anjomani Virmouni, Sara, Elder, George A., Tyson, Adam L., Dória, Maria Luisa, van Weverwijk, Antoinette, Soares, Renata F., Isacke, Clare M., Nicholson, Jeremy K., Glen, Robert C., Takats, Zoltan, Poulogiannis, George
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339148/ https://www.ncbi.nlm.nih.gov/pubmed/32559461 http://dx.doi.org/10.1016/j.cell.2020.05.053

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