Cargando…
miR‐126 reduces trastuzumab resistance by targeting PIK3R2 and regulating AKT/mTOR pathway in breast cancer cells
MicroRNAs (miRNAs) have been found to play a key role in drug resistance. In the current study, we aimed to explore the potential role of miR‐126 in trastuzumab resistance in breast cancer cells. We found that the trastuzumab‐resistant cell lines SKBR3/TR and BT474/TR had low expression of miR‐126 a...
Autores principales: | Fu, Rao, Tong, Jing‐Shan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339158/ https://www.ncbi.nlm.nih.gov/pubmed/32410348 http://dx.doi.org/10.1111/jcmm.15396 |
Ejemplares similares
-
miR-126 and miR-126*: New Players in Cancer
por: Meister, Jeannette, et al.
Publicado: (2010) -
Cotargeting of miR‐126‐3p and miR‐221‐3p inhibits PIK3R2 and PTEN, reducing lung cancer growth and metastasis by blocking AKT and CXCR4 signalling
por: Di Paolo, Daniela, et al.
Publicado: (2021) -
miR-122 and miR-199 synergistically promote autophagy in oral lichen planus by targeting the Akt/mTOR pathway
por: Wang, Liang, et al.
Publicado: (2019) -
miR-320a in serum exosomes promotes myocardial fibroblast proliferation via regulating the PIK3CA/Akt/mTOR signaling pathway in HEH2 cells
por: Wang, Qing-Gao, et al.
Publicado: (2021) -
miR-451a is underexpressed and targets AKT/mTOR pathway in papillary thyroid carcinoma
por: Minna, Emanuela, et al.
Publicado: (2016)