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Targeting lipid droplet lysophosphatidylcholine for cisplatin chemotherapy

This study aims to explore lipidic mechanism towards low‐density lipoprotein receptor (LDLR)‐mediated platinum chemotherapy resistance. By using the lipid profiling technology, LDLR knockdown was found to increase lysosomal lipids and decrease membranous lipid levels in EOC cells. LDLR knockdown als...

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Detalles Bibliográficos
Autores principales: Chen, Lumin, Ma, Wen‐Lung, Cheng, Wei‐Chung, Yang, Juan‐Cheng, Wang, Hsiao‐Ching, Su, Yu‐Ting, Ahmad, Azaj, Hung, Yao‐Ching, Chang, Wei‐Chun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339169/
https://www.ncbi.nlm.nih.gov/pubmed/32543783
http://dx.doi.org/10.1111/jcmm.15218