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Targeting lipid droplet lysophosphatidylcholine for cisplatin chemotherapy
This study aims to explore lipidic mechanism towards low‐density lipoprotein receptor (LDLR)‐mediated platinum chemotherapy resistance. By using the lipid profiling technology, LDLR knockdown was found to increase lysosomal lipids and decrease membranous lipid levels in EOC cells. LDLR knockdown als...
Autores principales: | Chen, Lumin, Ma, Wen‐Lung, Cheng, Wei‐Chung, Yang, Juan‐Cheng, Wang, Hsiao‐Ching, Su, Yu‐Ting, Ahmad, Azaj, Hung, Yao‐Ching, Chang, Wei‐Chun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339169/ https://www.ncbi.nlm.nih.gov/pubmed/32543783 http://dx.doi.org/10.1111/jcmm.15218 |
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