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Peroxisome proliferator‐activated receptor gamma‐ligand‐binding domain mutations associated with familial partial lipodystrophy type 3 disrupt human trophoblast fusion and fibroblast migration

The transcription factor peroxisome proliferator‐activated receptor gamma (PPARG) is essential for placental development, and alterations in its expression and/or activity are associated with human placental pathologies such as pre‐eclampsia or IUGR. However, the molecular regulation of PPARG in cyt...

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Detalles Bibliográficos
Autores principales: Shoaito, Hussein, Chauveau, Sabine, Gosseaume, Camille, Bourguet, William, Vigouroux, Corinne, Vatier, Camille, Pienkowski, Catherine, Fournier, Thierry, Degrelle, Séverine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339198/
https://www.ncbi.nlm.nih.gov/pubmed/32519441
http://dx.doi.org/10.1111/jcmm.15401

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