Focal adhesion kinase is activated by microtubule‐depolymerizing agents and regulates membrane blebbing in human endothelial cells

Microtubule‐depolymerizing agents can selectively disrupt tumor vessels via inducing endothelial membrane blebbing. However, the mechanism regulating blebbing is largely unknown. IMB5046 is a newly discovered microtubule‐depolymerizing agent. Here, the functions of focal adhesion kinase (FAK) during...

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Detalles Bibliográficos
Autores principales: Zheng, Yan‐Bo, Gong, Jian‐Hua, Zhen, Yong‐Su
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339229/
https://www.ncbi.nlm.nih.gov/pubmed/32452639
http://dx.doi.org/10.1111/jcmm.15273

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339229/
https://www.ncbi.nlm.nih.gov/pubmed/32452639
http://dx.doi.org/10.1111/jcmm.15273

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