Assessment of circulating tumor DNA in cerebrospinal fluid by whole exome sequencing to detect genomic alterations of glioblastoma

BACKGROUND: Cerebrospinal fluid (CSF) has been demonstrated as a better source of circulating tumor DNA (ctDNA) than plasma for brain tumors. However, it is unclear whether whole exome sequencing (WES) is qualified for detection of ctDNA in CSF. The aim of this study was to determine if assessment o...

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Detalles Bibliográficos
Autores principales: Duan, Hao, Hu, Ji-Long, Chen, Zheng-He, Li, Jue-Hui, He, Zhen-Qiang, Wang, Zhen-Ning, Zhang, Guan-Hua, Guo, Xiao-Yu, Liang, Lun, Mou, Yong-Gao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2020
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339330/
https://www.ncbi.nlm.nih.gov/pubmed/32558704
http://dx.doi.org/10.1097/CM9.0000000000000843

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