Cargando…

Targeted Muscle Reinnervation for Partial Hand Amputation

BACKGROUND: Targeted muscle reinnervation for the treatment of symptomatic neuromas after upper limb amputation has been described for shoulder disarticulation and for transhumeral and transradial amputations. Early clinical outcomes are promising and demonstrate a statistically significant reductio...

Descripción completa

Detalles Bibliográficos
Autores principales: Chepla, Kyle J., Wu-Fienberg, Yuewei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer Health 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339332/
https://www.ncbi.nlm.nih.gov/pubmed/32766082
http://dx.doi.org/10.1097/GOX.0000000000002946
_version_ 1783554866210144256
author Chepla, Kyle J.
Wu-Fienberg, Yuewei
author_facet Chepla, Kyle J.
Wu-Fienberg, Yuewei
author_sort Chepla, Kyle J.
collection PubMed
description BACKGROUND: Targeted muscle reinnervation for the treatment of symptomatic neuromas after upper limb amputation has been described for shoulder disarticulation and for transhumeral and transradial amputations. Early clinical outcomes are promising and demonstrate a statistically significant reduction in phantom limb pain and a decrease in residual limb pain. METHODS: We performed a cadaver dissection of the motor branches arising from the median and ulnar nerves to assess whether this technique could be applied to symptomatic neuromas after partial hand and finger amputations. RESULTS: After identification of all branches under 4.5x loupe magnification, we performed simulated transfers of digital nerves to lumbrical motor branches, common digital nerves to lumbrical motor branches or the recurrent motor branch, and the common sensory portion of the ulnar nerve to a hypothenar motor branch. CONCLUSIONS: The proximity of all sensory nerves to motor branches and the numerous redundant motor nerve targets available support our hypothesis that targeted muscle reinnervation is possible after partial hand or finger amputation. Further studies will be required to refine clinical indications and evaluate outcomes.
format Online
Article
Text
id pubmed-7339332
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Wolters Kluwer Health
record_format MEDLINE/PubMed
spelling pubmed-73393322020-08-05 Targeted Muscle Reinnervation for Partial Hand Amputation Chepla, Kyle J. Wu-Fienberg, Yuewei Plast Reconstr Surg Glob Open Hand/Peripheral Nerve BACKGROUND: Targeted muscle reinnervation for the treatment of symptomatic neuromas after upper limb amputation has been described for shoulder disarticulation and for transhumeral and transradial amputations. Early clinical outcomes are promising and demonstrate a statistically significant reduction in phantom limb pain and a decrease in residual limb pain. METHODS: We performed a cadaver dissection of the motor branches arising from the median and ulnar nerves to assess whether this technique could be applied to symptomatic neuromas after partial hand and finger amputations. RESULTS: After identification of all branches under 4.5x loupe magnification, we performed simulated transfers of digital nerves to lumbrical motor branches, common digital nerves to lumbrical motor branches or the recurrent motor branch, and the common sensory portion of the ulnar nerve to a hypothenar motor branch. CONCLUSIONS: The proximity of all sensory nerves to motor branches and the numerous redundant motor nerve targets available support our hypothesis that targeted muscle reinnervation is possible after partial hand or finger amputation. Further studies will be required to refine clinical indications and evaluate outcomes. Wolters Kluwer Health 2020-06-23 /pmc/articles/PMC7339332/ /pubmed/32766082 http://dx.doi.org/10.1097/GOX.0000000000002946 Text en Copyright © 2020 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of The American Society of Plastic Surgeons. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND) (http://creativecommons.org/licenses/by-nc-nd/4.0/) , where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.
spellingShingle Hand/Peripheral Nerve
Chepla, Kyle J.
Wu-Fienberg, Yuewei
Targeted Muscle Reinnervation for Partial Hand Amputation
title Targeted Muscle Reinnervation for Partial Hand Amputation
title_full Targeted Muscle Reinnervation for Partial Hand Amputation
title_fullStr Targeted Muscle Reinnervation for Partial Hand Amputation
title_full_unstemmed Targeted Muscle Reinnervation for Partial Hand Amputation
title_short Targeted Muscle Reinnervation for Partial Hand Amputation
title_sort targeted muscle reinnervation for partial hand amputation
topic Hand/Peripheral Nerve
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339332/
https://www.ncbi.nlm.nih.gov/pubmed/32766082
http://dx.doi.org/10.1097/GOX.0000000000002946
work_keys_str_mv AT cheplakylej targetedmusclereinnervationforpartialhandamputation
AT wufienbergyuewei targetedmusclereinnervationforpartialhandamputation