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NCSTN promotes hepatocellular carcinoma cell growth and metastasis via β-catenin activation in a Notch1/AKT dependent manner

BACKGROUND: Hepatocellular carcinoma is the third top cause of cancer-related mortalities worldwide. The prognosis of HCC patients remains poor due to rapid progression and high incidence of tumor recurrence. Nicastrin (NCSTN), a core subunit of γ-Secretase, has been reported to play a vital role in...

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Detalles Bibliográficos
Autores principales:	Li, Hui, Lan, Tian, Xu, Lin, Liu, Hailing, Wang, Jinju, Li, Jiaxin, Chen, Xiangzheng, Huang, Jiwei, Li, Xuefeng, Yuan, Kefei, Zeng, Yong, Wu, Hong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339515/ https://www.ncbi.nlm.nih.gov/pubmed/32631394 http://dx.doi.org/10.1186/s13046-020-01638-3

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