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Prevalence of dyslipidemia and associated risk factors among adults aged ≥35 years in northern China: a cross-sectional study

BACKGROUND: Cardiovascular disease (CVD) prevalence has increased continuously over the last 30 years in China. Dyslipidemia is an important modifiable risk factor in CVD. We aimed to collect current data on the prevalence of dyslipidemia in northern China and explore potential influencing factors....

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Autores principales: Xi, Yunfeng, Niu, Liwei, Cao, Ning, Bao, Han, Xu, Xiaoqian, Zhu, Hao, Yan, Tao, Zhang, Nan, Qiao, Liying, Han, Ke, Hang, Gai, Wang, Wenrui, Zhang, Xingguang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339536/
https://www.ncbi.nlm.nih.gov/pubmed/32631296
http://dx.doi.org/10.1186/s12889-020-09172-9
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author Xi, Yunfeng
Niu, Liwei
Cao, Ning
Bao, Han
Xu, Xiaoqian
Zhu, Hao
Yan, Tao
Zhang, Nan
Qiao, Liying
Han, Ke
Hang, Gai
Wang, Wenrui
Zhang, Xingguang
author_facet Xi, Yunfeng
Niu, Liwei
Cao, Ning
Bao, Han
Xu, Xiaoqian
Zhu, Hao
Yan, Tao
Zhang, Nan
Qiao, Liying
Han, Ke
Hang, Gai
Wang, Wenrui
Zhang, Xingguang
author_sort Xi, Yunfeng
collection PubMed
description BACKGROUND: Cardiovascular disease (CVD) prevalence has increased continuously over the last 30 years in China. Dyslipidemia is an important modifiable risk factor in CVD. We aimed to collect current data on the prevalence of dyslipidemia in northern China and explore potential influencing factors. METHODS: In this cross-sectional study, we selected a representative sample of 65,128 participants aged ≥35 years in Inner Mongolia during 2015–2017. All participants completed a questionnaire and were examined for risk factors. Dyslipidemia was defined according to 2016 Chinese guidelines for adults. The associated factors for dyslipidemia were estimated by multivariate logistic regression analysis. RESULTS: The age-standardized prevalence of dyslipidemia was 31.2% overall, with 4.3, 2.4, 14.7, and 17.4% for high total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), triglycerides (TG), and low high-density lipoprotein cholesterol (HDL-C), respectively. The dyslipidemia prevalence was significantly higher in men than women (37.9% vs. 27.5%, P < 0.001), but postmenopausal women had a higher prevalence of dyslipidemia components (except low HDL-C). Compared with Han participants, Mongol participants had a lower prevalence of dyslipidemia (29.1% vs. 31.4%, P < 0.001). Male sex, living in urban areas, Han ethnicity, smoking, obesity, central obesity, hypertension, and diabetes were all positively correlated with dyslipidemia; alcohol consumption was linked to lower risk of dyslipidemia. CONCLUSIONS: Our study revealed that dyslipidemia is a health problem in northern China. Greater efforts to prevent and manage dyslipidemia, especially in men under age 55 years, postmenopausal women, and people with unhealthy lifestyles or chronic diseases.
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spelling pubmed-73395362020-07-09 Prevalence of dyslipidemia and associated risk factors among adults aged ≥35 years in northern China: a cross-sectional study Xi, Yunfeng Niu, Liwei Cao, Ning Bao, Han Xu, Xiaoqian Zhu, Hao Yan, Tao Zhang, Nan Qiao, Liying Han, Ke Hang, Gai Wang, Wenrui Zhang, Xingguang BMC Public Health Research Article BACKGROUND: Cardiovascular disease (CVD) prevalence has increased continuously over the last 30 years in China. Dyslipidemia is an important modifiable risk factor in CVD. We aimed to collect current data on the prevalence of dyslipidemia in northern China and explore potential influencing factors. METHODS: In this cross-sectional study, we selected a representative sample of 65,128 participants aged ≥35 years in Inner Mongolia during 2015–2017. All participants completed a questionnaire and were examined for risk factors. Dyslipidemia was defined according to 2016 Chinese guidelines for adults. The associated factors for dyslipidemia were estimated by multivariate logistic regression analysis. RESULTS: The age-standardized prevalence of dyslipidemia was 31.2% overall, with 4.3, 2.4, 14.7, and 17.4% for high total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), triglycerides (TG), and low high-density lipoprotein cholesterol (HDL-C), respectively. The dyslipidemia prevalence was significantly higher in men than women (37.9% vs. 27.5%, P < 0.001), but postmenopausal women had a higher prevalence of dyslipidemia components (except low HDL-C). Compared with Han participants, Mongol participants had a lower prevalence of dyslipidemia (29.1% vs. 31.4%, P < 0.001). Male sex, living in urban areas, Han ethnicity, smoking, obesity, central obesity, hypertension, and diabetes were all positively correlated with dyslipidemia; alcohol consumption was linked to lower risk of dyslipidemia. CONCLUSIONS: Our study revealed that dyslipidemia is a health problem in northern China. Greater efforts to prevent and manage dyslipidemia, especially in men under age 55 years, postmenopausal women, and people with unhealthy lifestyles or chronic diseases. BioMed Central 2020-07-06 /pmc/articles/PMC7339536/ /pubmed/32631296 http://dx.doi.org/10.1186/s12889-020-09172-9 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Research Article
Xi, Yunfeng
Niu, Liwei
Cao, Ning
Bao, Han
Xu, Xiaoqian
Zhu, Hao
Yan, Tao
Zhang, Nan
Qiao, Liying
Han, Ke
Hang, Gai
Wang, Wenrui
Zhang, Xingguang
Prevalence of dyslipidemia and associated risk factors among adults aged ≥35 years in northern China: a cross-sectional study
title Prevalence of dyslipidemia and associated risk factors among adults aged ≥35 years in northern China: a cross-sectional study
title_full Prevalence of dyslipidemia and associated risk factors among adults aged ≥35 years in northern China: a cross-sectional study
title_fullStr Prevalence of dyslipidemia and associated risk factors among adults aged ≥35 years in northern China: a cross-sectional study
title_full_unstemmed Prevalence of dyslipidemia and associated risk factors among adults aged ≥35 years in northern China: a cross-sectional study
title_short Prevalence of dyslipidemia and associated risk factors among adults aged ≥35 years in northern China: a cross-sectional study
title_sort prevalence of dyslipidemia and associated risk factors among adults aged ≥35 years in northern china: a cross-sectional study
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339536/
https://www.ncbi.nlm.nih.gov/pubmed/32631296
http://dx.doi.org/10.1186/s12889-020-09172-9
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