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Downregulation of microRNA-106a-5p alleviates ox-LDL-mediated endothelial cell injury by targeting STAT3

The apoptosis of endothelial cells (ECs) induced by oxidized low-density lipoprotein (ox-LDL) is an important contributing factor in the pathogenesis of atherosclerosis. It has been reported that microRNA (miR)-106a-5p is overexpressed in atherosclerotic plaques and involved in angiogenesis. However...

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Detalles Bibliográficos
Autores principales: Hu, Ying, Xu, Rong, He, Yue, Zhao, Zhibo, Mao, Xudong, Lin, Ling, Hu, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339537/
https://www.ncbi.nlm.nih.gov/pubmed/32626987
http://dx.doi.org/10.3892/mmr.2020.11147