Long non-coding RNA ANRIL knockdown suppresses apoptosis and pro-inflammatory cytokines while enhancing neurite outgrowth via binding microRNA-125a in a cellular model of Alzheimer's disease

The present study aimed to investigate the effect of the long non-coding RNA antisense non-coding RNA in the INK4 locus (lnc-ANRIL) knockdown on apoptosis, neurite outgrowth and inflammation based on a PC12 cellular Alzheimer's disease (AD) model. A cellular AD model was constructed by treating...

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Detalles Bibliográficos
Autores principales: Zhou, Bingling, Li, Lijuan, Qiu, Xin, Wu, Jiashun, Xu, Lei, Shao, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339647/
https://www.ncbi.nlm.nih.gov/pubmed/32626959
http://dx.doi.org/10.3892/mmr.2020.11203

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