Cargando…

Bioinformatic analysis of the potential molecular mechanism of PAK7 expression in glioblastoma

The present study aimed to determine the potential molecular mechanisms underlying p21 (RAC1)-activated kinase 7 (PAK7) expression in glioblastoma (GBM) and evaluate candidate prognosis biomarkers for GBM. Gene expression data from patients with GBM, including 144 tumor samples and 5 normal brain sa...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Xuefeng, Liu, Shuang, Shao, Zhengkai, Zhang, Penghai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339666/ https://www.ncbi.nlm.nih.gov/pubmed/32626960 http://dx.doi.org/10.3892/mmr.2020.11206

Ejemplares similares

Identification of potential crucial genes and molecular mechanisms in glioblastoma multiforme by bioinformatics analysis
por: Chen, Xiaojie, et al.
Publicado: (2020)

Identification of the potential oncogenes in glioblastoma based on bioinformatic analysis and elucidation of the underlying mechanisms
por: Zhang, Yong, et al.
Publicado: (2018)

Bioinformatics analysis of potential core genes for glioblastoma
por: Zhang, Yu, et al.
Publicado: (2020)

Functional Deficits in Pak5, Pak6 and Pak5/Pak6 Knockout Mice
por: Furnari, Melody A., et al.
Publicado: (2013)

Bioinformatics analysis of potential glioblastoma circular RNA sponge network
por: Zhao, Liwen, et al.
Publicado: (2022)

Identification of Potential Biomarkers of Platelet RNA in Glioblastoma by Bioinformatics Analysis
por: Chen, Xianjun, et al.
Publicado: (2022)

Tetramethylpyrazine Protects Neurons from Oxygen-Glucose Deprivation-Induced Death
por: Shao, Zhengkai, et al.
Publicado: (2017)

Gene Expression Analysis of Pak Choi in Response to Vernalization
por: Sun, Mengxia, et al.
Publicado: (2015)

PAK1, PAK1Δ15, and PAK2: similarities, differences and mutual interactions
por: Grebeňová, Dana, et al.
Publicado: (2019)

Bioinformatics Analysis of the Molecular Mechanism and Potential Treatment Target of Ankylosing Spondylitis
por: Meng, Fanyan, et al.
Publicado: (2021)

Identification of key biomarkers and potential molecular mechanisms in lung cancer by bioinformatics analysis
por: Li, Zhenhua, et al.
Publicado: (2019)

The Predictive Value of PAK7 Mutation for Immune Checkpoint Inhibitors Therapy in Non-Small Cell Cancer
por: Zeng, Hao, et al.
Publicado: (2022)

Differential roles and regulation of the protein kinases PAK4, PAK5 and PAK6 in melanoma cells
por: Murugesan, Gavuthami, et al.
Publicado: (2022)

Identification of Potential Biomarkers in Glioblastoma through Bioinformatic Analysis and Evaluating Their Prognostic Value
por: Zhou, Yangmei, et al.
Publicado: (2019)

Identification of hub genes and potential molecular mechanisms in gastric cancer by integrated bioinformatics analysis
por: Cao, Ling, et al.
Publicado: (2018)

Crystal Structures of the p21-Activated Kinases PAK4, PAK5, and PAK6 Reveal Catalytic Domain Plasticity of Active Group II PAKs
por: Eswaran, Jeyanthy, et al.
Publicado: (2007)

Identification of potential microRNAs in glioblastoma using bioinformatic analysis and prognostic evaluation
por: Sun, Zhenwei, et al.
Publicado: (2020)

Investigation of Potential Genetic Biomarkers and Molecular Mechanism of Ulcerative Colitis Utilizing Bioinformatics Analysis
por: Zhang, Jiaqi, et al.
Publicado: (2020)

Direct Interaction between AR and PAK6 in Androgen-Stimulated PAK6 Activation
por: Liu, Xia, et al.
Publicado: (2013)

RAB7A Regulates Vimentin Phosphorylation through AKT and PAK
por: Romano, Roberta, et al.
Publicado: (2021)

PAK Signaling in Oncogenesis
por: Molli, Poonam R., et al.
Publicado: (2009)

PAK signaling in cancer
por: Ye, Diana Zi, et al.
Publicado: (2012)

Expansion of BCR/ABL1 (+) cells requires PAK2 but not PAK1
por: Edlinger, Leo, et al.
Publicado: (2017)

PAK4 signaling in health and disease: defining the PAK4–CREB axis
por: Won, So-Yoon, et al.
Publicado: (2019)

PAK1 and PAK4 as therapeutic targets for Ewing sarcoma: a commentary
por: Parks, Sydney E., et al.
Publicado: (2021)

Pak1 Kinase Promotes Activated T Cell Trafficking by Regulating the Expression of L-Selectin and CCR7
por: Dios-Esponera, Ana, et al.
Publicado: (2019)

Investigating age-induced differentially expressed genes and potential molecular mechanisms in osteosarcoma based on integrated bioinformatics analysis
por: Wang, Jian-Sheng, et al.
Publicado: (2019)

Identification of differentially expressed genes regulated by transcription factors in glioblastomas by bioinformatics analysis
por: WEI, BO, et al.
Publicado: (2015)

Prediction and Analysis of Key Genes in Glioblastoma Based on Bioinformatics
por: Long, Hao, et al.
Publicado: (2017)

Effect of PAK Inhibition on Cell Mechanics Depends on Rac1
por: Mierke, Claudia Tanja, et al.
Publicado: (2020)

Identification of Core Genes and Screening of Potential Targets in Glioblastoma Multiforme by Integrated Bioinformatic Analysis
por: Yang, Ji’an, et al.
Publicado: (2021)

Efficient Inhibition of Human Glioma Development by RNA Interference-Mediated Silencing of PAK5
por: Gu, Xuefeng, et al.
Publicado: (2015)

p21-activated kinase 1: PAK'ed with potential
por: Ong, Christy C., et al.
Publicado: (2011)

PAK1-blockers: Potential Therapeutics against COVID-19()
por: Maruta, Hiroshi, et al.
Publicado: (2020)

Bioinformatic analysis of the molecular mechanisms underlying the progression of bone defects
por: Liu, Hao, et al.
Publicado: (2023)

Integrated Analysis of Hi-C and RNA-Seq Reveals the Molecular Mechanism of Autopolyploid Growth Advantages in Pak Choi (Brassica rapa ssp. chinensis)
por: Wu, Huiyuan, et al.
Publicado: (2022)

Gene expression profile analysis of colorectal cancer to investigate potential mechanisms using bioinformatics
por: Kou, Yubin, et al.
Publicado: (2015)

A bioinformatic analysis study of m(7)G regulator-mediated methylation modification patterns and tumor microenvironment infiltration in glioblastoma
por: Wu, Xinrui, et al.
Publicado: (2022)

Integrated bioinformatic analysis reveals the underlying molecular mechanism of and potential drugs for pulmonary arterial hypertension
por: Dong, Haoru, et al.
Publicado: (2021)

Bioinformatics analysis of microenvironment-related genes associated with radioresistance in glioblastoma
por: Liu, Yun, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_9hg29tb4sds993qv1vf7103il8