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Saikosaponin D inhibits autophagosome-lysosome fusion and induces autophagy-independent apoptosis in MDA-MB-231 breast cancer cells

The present study aimed to explore the effect of Saikosaponin D (SSD) and its underlying mechanism on apoptosis and autophagy in human breast cancer MDA-MB-231 cells. MTT assay, flow cytometry, western blotting and confocal fluorescence microscopy detection were employed. SSD, a kind of triterpenoid...

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Detalles Bibliográficos
Autores principales:	Fu, Ruoqiu, Zhang, Lin, Li, Yuanyuan, Li, Bin, Ming, Yue, Li, Zhiwei, Xing, Haiyan, Chen, Jianhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339770/ https://www.ncbi.nlm.nih.gov/pubmed/32468000 http://dx.doi.org/10.3892/mmr.2020.11155

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