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TAK-242 exerts a neuroprotective effect via suppression of the TLR4/MyD88/TRIF/NF-κB signaling pathway in a neonatal hypoxic-ischemic encephalopathy rat model

Neonatal hypoxic-ischemic encephalopathy (HIE) is one of the main causes of death and nervous system damage in neonates. The aim of the present study was to investigate the effect of the Toll-like receptor 4 (TLR4) antagonist TAK-242 on HIE. The Rice-Vannucci method was used for ligation of the left...

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Detalles Bibliográficos
Autores principales:	Jiang, Lijun, Xu, Zhenxing, Li, Hui, Wu, Mingfu, Wang, Fudong, Liu, Shunying, Tao, Jianlan, Feng, Xing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	D.A. Spandidos 2020
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339810/ https://www.ncbi.nlm.nih.gov/pubmed/32627010 http://dx.doi.org/10.3892/mmr.2020.11220

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