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NCTD elicits proapoptotic and antiglycolytic effects on colorectal cancer cells via modulation of Fam46c expression and inhibition of ERK1/2 signaling

Colorectal cancer is a digestive tract malignancy and the third leading cause of cancer-related mortality worldwide. Norcantharidin (NCTD), the demethylated form of cantharidin, has been reported to possess anticancer properties. Family-with-sequence-similarity-46c (Fam46c), a non-canonical poly(A)...

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Detalles Bibliográficos
Autores principales: Zhang, Shiqiang, Yang, Yun, Hua, Yunwei, Hu, Chen, Zhong, Yi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339822/
https://www.ncbi.nlm.nih.gov/pubmed/32468032
http://dx.doi.org/10.3892/mmr.2020.11151