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Is there a relationship between epicardial fat tissue thickness and Tp-Te/QT ratio in healthy individuals?
INTRODUCTION: Epicardial fat is a tissue that releases many proinflammatory and atherogenic mediators, with endocrine and paracrine effects on the heart. In this study, the implication of the EFT thickness (EFTt) on transmural dispersion of repolarisation (TDR) was analysed utilizing the T-wave peak...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Termedia Publishing House
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339868/ https://www.ncbi.nlm.nih.gov/pubmed/32665987 http://dx.doi.org/10.5114/aoms.2020.96147 |
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author | Yılmaz, Mücahid Kayançiçek, Hidayet Gözel, Nevzat Kurtoğlu, Ertuğrul Seçen, Özlem Öner, Pınar Çekici, Yusuf Bilen, Mehmet Nail Demirkıran, Suat Uku, Ökkeş |
author_facet | Yılmaz, Mücahid Kayançiçek, Hidayet Gözel, Nevzat Kurtoğlu, Ertuğrul Seçen, Özlem Öner, Pınar Çekici, Yusuf Bilen, Mehmet Nail Demirkıran, Suat Uku, Ökkeş |
author_sort | Yılmaz, Mücahid |
collection | PubMed |
description | INTRODUCTION: Epicardial fat is a tissue that releases many proinflammatory and atherogenic mediators, with endocrine and paracrine effects on the heart. In this study, the implication of the EFT thickness (EFTt) on transmural dispersion of repolarisation (TDR) was analysed utilizing the T-wave peak to end interval (Tp-Te), the Tp-Te dispersion (Tp-Te (d)), and the Tp-Te/QT ratio. MATERIAL AND METHODS: One thousand seven hundred and thirteen subjects were enrolled in the research. The subjects were chosen to be healthy individuals, without any cardiovascular/systemic disorders or risk factors for atherosclerosis. Transthoracic echocardiography (TTE) was applied to all subjects, and EFTt was measured in both diastole and systole. The ECG measurements were taken from standard 12-lead surface ECG. RESULTS: Correlation analysis revealed that the EFTt is highly associated with the Tp-Te interval, Tp-Te/QT ratio, Tp-Te (d), increasing age, body mass index (BMI), body surface area (BSA), left ventricular (LV) mass, LV mass index, plasma glucose during fasting, triglycerides, and low-density lipoprotein cholesterol. CONCLUSIONS: The study results showed that increased EFTt was associated with increased TDR values of Tp-Te, Tp-Te (d), and Tp-Te/QT ratio, even in the absence of other factors that could increase TDR and EFTt. Therefore, it can be stated that increased EFTt may cause an increase the risk for ventricular arrhythmia. |
format | Online Article Text |
id | pubmed-7339868 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Termedia Publishing House |
record_format | MEDLINE/PubMed |
spelling | pubmed-73398682020-07-13 Is there a relationship between epicardial fat tissue thickness and Tp-Te/QT ratio in healthy individuals? Yılmaz, Mücahid Kayançiçek, Hidayet Gözel, Nevzat Kurtoğlu, Ertuğrul Seçen, Özlem Öner, Pınar Çekici, Yusuf Bilen, Mehmet Nail Demirkıran, Suat Uku, Ökkeş Arch Med Sci Atheroscler Dis Clinical Research INTRODUCTION: Epicardial fat is a tissue that releases many proinflammatory and atherogenic mediators, with endocrine and paracrine effects on the heart. In this study, the implication of the EFT thickness (EFTt) on transmural dispersion of repolarisation (TDR) was analysed utilizing the T-wave peak to end interval (Tp-Te), the Tp-Te dispersion (Tp-Te (d)), and the Tp-Te/QT ratio. MATERIAL AND METHODS: One thousand seven hundred and thirteen subjects were enrolled in the research. The subjects were chosen to be healthy individuals, without any cardiovascular/systemic disorders or risk factors for atherosclerosis. Transthoracic echocardiography (TTE) was applied to all subjects, and EFTt was measured in both diastole and systole. The ECG measurements were taken from standard 12-lead surface ECG. RESULTS: Correlation analysis revealed that the EFTt is highly associated with the Tp-Te interval, Tp-Te/QT ratio, Tp-Te (d), increasing age, body mass index (BMI), body surface area (BSA), left ventricular (LV) mass, LV mass index, plasma glucose during fasting, triglycerides, and low-density lipoprotein cholesterol. CONCLUSIONS: The study results showed that increased EFTt was associated with increased TDR values of Tp-Te, Tp-Te (d), and Tp-Te/QT ratio, even in the absence of other factors that could increase TDR and EFTt. Therefore, it can be stated that increased EFTt may cause an increase the risk for ventricular arrhythmia. Termedia Publishing House 2020-06-05 /pmc/articles/PMC7339868/ /pubmed/32665987 http://dx.doi.org/10.5114/aoms.2020.96147 Text en Copyright © 2020 Termedia & Banach http://creativecommons.org/licenses/by-nc-sa/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International (CC BY-NC-SA 4.0) License (http://creativecommons.org/licenses/by-nc-sa/4.0/), allowing third parties to copy and redistribute the material in any medium or format and to remix, transform, and build upon the material, provided the original work is properly cited and states its license. |
spellingShingle | Clinical Research Yılmaz, Mücahid Kayançiçek, Hidayet Gözel, Nevzat Kurtoğlu, Ertuğrul Seçen, Özlem Öner, Pınar Çekici, Yusuf Bilen, Mehmet Nail Demirkıran, Suat Uku, Ökkeş Is there a relationship between epicardial fat tissue thickness and Tp-Te/QT ratio in healthy individuals? |
title | Is there a relationship between epicardial fat tissue thickness and Tp-Te/QT ratio in healthy individuals? |
title_full | Is there a relationship between epicardial fat tissue thickness and Tp-Te/QT ratio in healthy individuals? |
title_fullStr | Is there a relationship between epicardial fat tissue thickness and Tp-Te/QT ratio in healthy individuals? |
title_full_unstemmed | Is there a relationship between epicardial fat tissue thickness and Tp-Te/QT ratio in healthy individuals? |
title_short | Is there a relationship between epicardial fat tissue thickness and Tp-Te/QT ratio in healthy individuals? |
title_sort | is there a relationship between epicardial fat tissue thickness and tp-te/qt ratio in healthy individuals? |
topic | Clinical Research |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339868/ https://www.ncbi.nlm.nih.gov/pubmed/32665987 http://dx.doi.org/10.5114/aoms.2020.96147 |
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