Notch3 Modulates Cardiac Fibroblast Proliferation, Apoptosis, and Fibroblast to Myofibroblast Transition via Negative Regulation of the RhoA/ROCK/Hif1α Axis

Cardiac fibrosis is a common pathological process in multiple cardiovascular diseases, including myocardial infarction (MI). Abnormal cardiac fibroblast (CF) activity is a key event in cardiac fibrosis. Although the Notch signaling pathway has been reported to play a vital role in protection from ca...

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Detalles Bibliográficos
Autores principales: Shi, Jianli, Xiao, Peilin, Liu, Xiaoli, Chen, Yunlin, Xu, Yanping, Fan, Jinqi, Yin, Yuehui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2020
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339920/
https://www.ncbi.nlm.nih.gov/pubmed/32695015
http://dx.doi.org/10.3389/fphys.2020.00669

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339920/
https://www.ncbi.nlm.nih.gov/pubmed/32695015
http://dx.doi.org/10.3389/fphys.2020.00669

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