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Notch3 Modulates Cardiac Fibroblast Proliferation, Apoptosis, and Fibroblast to Myofibroblast Transition via Negative Regulation of the RhoA/ROCK/Hif1α Axis
Cardiac fibrosis is a common pathological process in multiple cardiovascular diseases, including myocardial infarction (MI). Abnormal cardiac fibroblast (CF) activity is a key event in cardiac fibrosis. Although the Notch signaling pathway has been reported to play a vital role in protection from ca...
Autores principales: | Shi, Jianli, Xiao, Peilin, Liu, Xiaoli, Chen, Yunlin, Xu, Yanping, Fan, Jinqi, Yin, Yuehui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7339920/ https://www.ncbi.nlm.nih.gov/pubmed/32695015 http://dx.doi.org/10.3389/fphys.2020.00669 |
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