Multiple sclerosis following SARS-CoV-2 infection

SARS-CoV-2 infection can produce neurological features. The most common are headache, anosmia and dysgeusia but patients may also develop other central nervous system (CNS) injuries. We present a patient affected by Covid-19 who initially consulted for decreased visual acuity. The MRI showed inflamm...

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Autores principales: Palao, M., Fernández-Díaz, E., Gracia-Gil, J., Romero-Sánchez, C.M., Díaz-Maroto, I., Segura, T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier B.V. 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7340057/
https://www.ncbi.nlm.nih.gov/pubmed/32698095
http://dx.doi.org/10.1016/j.msard.2020.102377
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author Palao, M.
Fernández-Díaz, E.
Gracia-Gil, J.
Romero-Sánchez, C.M.
Díaz-Maroto, I.
Segura, T.
author_facet Palao, M.
Fernández-Díaz, E.
Gracia-Gil, J.
Romero-Sánchez, C.M.
Díaz-Maroto, I.
Segura, T.
author_sort Palao, M.
collection PubMed
description SARS-CoV-2 infection can produce neurological features. The most common are headache, anosmia and dysgeusia but patients may also develop other central nervous system (CNS) injuries. We present a patient affected by Covid-19 who initially consulted for decreased visual acuity. The MRI showed inflammation in the right optic nerve and demyelinating lesions in the CNS. We speculate that an immune mechanism induced by SARS-CoV-2, which can activate lymphocytes and an inflammatory response, plays a role in the clinical onset of the disease. This pathogen may be associated with either the triggering or the exacerbation of inflammatory/demyelinating disease.
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spelling pubmed-73400572020-07-07 Multiple sclerosis following SARS-CoV-2 infection Palao, M. Fernández-Díaz, E. Gracia-Gil, J. Romero-Sánchez, C.M. Díaz-Maroto, I. Segura, T. Mult Scler Relat Disord Original Article SARS-CoV-2 infection can produce neurological features. The most common are headache, anosmia and dysgeusia but patients may also develop other central nervous system (CNS) injuries. We present a patient affected by Covid-19 who initially consulted for decreased visual acuity. The MRI showed inflammation in the right optic nerve and demyelinating lesions in the CNS. We speculate that an immune mechanism induced by SARS-CoV-2, which can activate lymphocytes and an inflammatory response, plays a role in the clinical onset of the disease. This pathogen may be associated with either the triggering or the exacerbation of inflammatory/demyelinating disease. Elsevier B.V. 2020-10 2020-07-07 /pmc/articles/PMC7340057/ /pubmed/32698095 http://dx.doi.org/10.1016/j.msard.2020.102377 Text en © 2020 Elsevier B.V. All rights reserved. Since January 2020 Elsevier has created a COVID-19 resource centre with free information in English and Mandarin on the novel coronavirus COVID-19. The COVID-19 resource centre is hosted on Elsevier Connect, the company's public news and information website. Elsevier hereby grants permission to make all its COVID-19-related research that is available on the COVID-19 resource centre - including this research content - immediately available in PubMed Central and other publicly funded repositories, such as the WHO COVID database with rights for unrestricted research re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for free by Elsevier for as long as the COVID-19 resource centre remains active.
spellingShingle Original Article
Palao, M.
Fernández-Díaz, E.
Gracia-Gil, J.
Romero-Sánchez, C.M.
Díaz-Maroto, I.
Segura, T.
Multiple sclerosis following SARS-CoV-2 infection
title Multiple sclerosis following SARS-CoV-2 infection
title_full Multiple sclerosis following SARS-CoV-2 infection
title_fullStr Multiple sclerosis following SARS-CoV-2 infection
title_full_unstemmed Multiple sclerosis following SARS-CoV-2 infection
title_short Multiple sclerosis following SARS-CoV-2 infection
title_sort multiple sclerosis following sars-cov-2 infection
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7340057/
https://www.ncbi.nlm.nih.gov/pubmed/32698095
http://dx.doi.org/10.1016/j.msard.2020.102377
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