Physiological and pathological insights into exosomes in the brain

Exosomes are small vesicles secreted by all cell types in the brain and play a role in cell-cell communication through the transfer of cargo or encapsulation. Exosomes in the brain have considerable impact on neuronal development, activation, and regeneration. In addition, exosomes are reported to b...

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Autores principales: Li, Xiao-Hui, Zhang, Juan, Li, Ding-Feng, Wu, Wei, Xie, Zhong-Wen, Liu, Qiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Science Press 2020
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7340524/
https://www.ncbi.nlm.nih.gov/pubmed/32400978
http://dx.doi.org/10.24272/j.issn.2095-8137.2020.043
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author Li, Xiao-Hui
Zhang, Juan
Li, Ding-Feng
Wu, Wei
Xie, Zhong-Wen
Liu, Qiang
author_facet Li, Xiao-Hui
Zhang, Juan
Li, Ding-Feng
Wu, Wei
Xie, Zhong-Wen
Liu, Qiang
author_sort Li, Xiao-Hui
collection PubMed
description Exosomes are small vesicles secreted by all cell types in the brain and play a role in cell-cell communication through the transfer of cargo or encapsulation. Exosomes in the brain have considerable impact on neuronal development, activation, and regeneration. In addition, exosomes are reported to be involved in the onset and propagation of various neurodegenerative diseases. In this review, we discuss the content of exosomes derived from major cell types in the brain, and their function under physiological and pathological conditions.
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spelling pubmed-73405242020-07-15 Physiological and pathological insights into exosomes in the brain Li, Xiao-Hui Zhang, Juan Li, Ding-Feng Wu, Wei Xie, Zhong-Wen Liu, Qiang Zool Res Review Exosomes are small vesicles secreted by all cell types in the brain and play a role in cell-cell communication through the transfer of cargo or encapsulation. Exosomes in the brain have considerable impact on neuronal development, activation, and regeneration. In addition, exosomes are reported to be involved in the onset and propagation of various neurodegenerative diseases. In this review, we discuss the content of exosomes derived from major cell types in the brain, and their function under physiological and pathological conditions. Science Press 2020-07-18 /pmc/articles/PMC7340524/ /pubmed/32400978 http://dx.doi.org/10.24272/j.issn.2095-8137.2020.043 Text en Editorial Office of Zoological Research, Kunming Institute of Zoology, Chinese Academy of Sciences https://creativecommons.org/licenses/by-nc/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) ), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review
Li, Xiao-Hui
Zhang, Juan
Li, Ding-Feng
Wu, Wei
Xie, Zhong-Wen
Liu, Qiang
Physiological and pathological insights into exosomes in the brain
title Physiological and pathological insights into exosomes in the brain
title_full Physiological and pathological insights into exosomes in the brain
title_fullStr Physiological and pathological insights into exosomes in the brain
title_full_unstemmed Physiological and pathological insights into exosomes in the brain
title_short Physiological and pathological insights into exosomes in the brain
title_sort physiological and pathological insights into exosomes in the brain
topic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7340524/
https://www.ncbi.nlm.nih.gov/pubmed/32400978
http://dx.doi.org/10.24272/j.issn.2095-8137.2020.043
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