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Efficacy of the FDA nozzle benchmark and the lattice Boltzmann method for the analysis of biomedical flows in transitional regime
Flows through medical devices as well as in anatomical vessels despite being at moderate Reynolds number may exhibit transitional or even turbulent character. In order to validate numerical methods and codes used for biomedical flow computations, the US Food and Drug Administration (FDA) established...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer Berlin Heidelberg
2020
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7340647/ https://www.ncbi.nlm.nih.gov/pubmed/32507933 http://dx.doi.org/10.1007/s11517-020-02188-8 |
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author | Jain, Kartik |
author_facet | Jain, Kartik |
author_sort | Jain, Kartik |
collection | PubMed |
description | Flows through medical devices as well as in anatomical vessels despite being at moderate Reynolds number may exhibit transitional or even turbulent character. In order to validate numerical methods and codes used for biomedical flow computations, the US Food and Drug Administration (FDA) established an experimental benchmark, which was a pipe with gradual contraction and sudden expansion representing a nozzle. The experimental results for various Reynolds numbers ranging from 500 to 6500 were publicly released. Previous and recent computational investigations of flow in the FDA nozzle found limitations in various CFD approaches and some even questioned the adequacy of the benchmark itself. This communication reports the results of a lattice Boltzmann method (LBM) – based direct numerical simulation (DNS) approach applied to the FDA nozzle benchmark for transitional cases of Reynolds numbers 2000 and 3500. The goal is to evaluate if a simple off the shelf LBM would predict the experimental results without the use of complex models or synthetic turbulence at the inflow. LBM computations with various spatial and temporal resolutions are performed—in the extremities of 45 million to 2.88 billion lattice cells—executed respectively on 32 CPU cores of a desktop to more than 300,000 cores of a modern supercomputer to explore and characterize miniscule flow details and quantify Kolmogorov scales. The LBM simulations transition to turbulence at a Reynolds number 2000 like the FDA’s experiments and acceptable agreement in jet breakdown locations, average velocity, shear stress, and pressure is found for both the Reynolds numbers. [Figure: see text] ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s11517-020-02188-8) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-7340647 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-73406472020-07-09 Efficacy of the FDA nozzle benchmark and the lattice Boltzmann method for the analysis of biomedical flows in transitional regime Jain, Kartik Med Biol Eng Comput Original Article Flows through medical devices as well as in anatomical vessels despite being at moderate Reynolds number may exhibit transitional or even turbulent character. In order to validate numerical methods and codes used for biomedical flow computations, the US Food and Drug Administration (FDA) established an experimental benchmark, which was a pipe with gradual contraction and sudden expansion representing a nozzle. The experimental results for various Reynolds numbers ranging from 500 to 6500 were publicly released. Previous and recent computational investigations of flow in the FDA nozzle found limitations in various CFD approaches and some even questioned the adequacy of the benchmark itself. This communication reports the results of a lattice Boltzmann method (LBM) – based direct numerical simulation (DNS) approach applied to the FDA nozzle benchmark for transitional cases of Reynolds numbers 2000 and 3500. The goal is to evaluate if a simple off the shelf LBM would predict the experimental results without the use of complex models or synthetic turbulence at the inflow. LBM computations with various spatial and temporal resolutions are performed—in the extremities of 45 million to 2.88 billion lattice cells—executed respectively on 32 CPU cores of a desktop to more than 300,000 cores of a modern supercomputer to explore and characterize miniscule flow details and quantify Kolmogorov scales. The LBM simulations transition to turbulence at a Reynolds number 2000 like the FDA’s experiments and acceptable agreement in jet breakdown locations, average velocity, shear stress, and pressure is found for both the Reynolds numbers. [Figure: see text] ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (10.1007/s11517-020-02188-8) contains supplementary material, which is available to authorized users. Springer Berlin Heidelberg 2020-06-07 2020 /pmc/articles/PMC7340647/ /pubmed/32507933 http://dx.doi.org/10.1007/s11517-020-02188-8 Text en © The Author(s) 2020 Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Original Article Jain, Kartik Efficacy of the FDA nozzle benchmark and the lattice Boltzmann method for the analysis of biomedical flows in transitional regime |
title | Efficacy of the FDA nozzle benchmark and the lattice Boltzmann method for the analysis of biomedical flows in transitional regime |
title_full | Efficacy of the FDA nozzle benchmark and the lattice Boltzmann method for the analysis of biomedical flows in transitional regime |
title_fullStr | Efficacy of the FDA nozzle benchmark and the lattice Boltzmann method for the analysis of biomedical flows in transitional regime |
title_full_unstemmed | Efficacy of the FDA nozzle benchmark and the lattice Boltzmann method for the analysis of biomedical flows in transitional regime |
title_short | Efficacy of the FDA nozzle benchmark and the lattice Boltzmann method for the analysis of biomedical flows in transitional regime |
title_sort | efficacy of the fda nozzle benchmark and the lattice boltzmann method for the analysis of biomedical flows in transitional regime |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7340647/ https://www.ncbi.nlm.nih.gov/pubmed/32507933 http://dx.doi.org/10.1007/s11517-020-02188-8 |
work_keys_str_mv | AT jainkartik efficacyofthefdanozzlebenchmarkandthelatticeboltzmannmethodfortheanalysisofbiomedicalflowsintransitionalregime |