Cargando…

Overexpression of Purinergic P2X4 Receptors in Hippocampus Rescues Memory Impairment in Rats with Type 2 Diabetes

Purinergic receptors have been reported to be involved in brain disorders. In this study, we explored their roles and mechanisms underlying the memory impairment in rats with type 2 diabetes mellitus (T2DM). T2DM rats exhibited a worse performance in the T-maze and Morris water maze (MWM) than contr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Ping-An, Sun, Qian, Li, Yong-Chang, Weng, Rui-Xia, Wu, Rui, Zhang, Hong-Hong, Xu, Guang-Yin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Singapore 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7340685/ https://www.ncbi.nlm.nih.gov/pubmed/32198702 http://dx.doi.org/10.1007/s12264-020-00478-7

Ejemplares similares

Overexpression of EphB2 in hippocampus rescues impaired NMDA receptors trafficking and cognitive dysfunction in Alzheimer model
por: Hu, Rui, et al.
Publicado: (2017)

Pathophysiological Role of Purinergic P2X Receptors in Digestive System Diseases
por: An, Qimin, et al.
Publicado: (2021)

Analysis of Spatial and Temporal Distribution of Purinergic P2 Receptors in the Mouse Hippocampus
por: Lommen, Julian, et al.
Publicado: (2021)

Select Overexpression of Homer1a in Dorsal Hippocampus Impairs Spatial Working Memory
por: Celikel, Tansu, et al.
Publicado: (2007)

P2X3 purinergic receptor overexpression is associated with poor recurrence-free survival in hepatocellular carcinoma patients
por: Maynard, Janielle P., et al.
Publicado: (2015)

Purinergic 2X7 Receptor is Involved in the Podocyte Damage of Obesity-Related Glomerulopathy via Activating Nucleotide-Binding and Oligomerization Domain-Like Receptor Protein 3 Inflammasome
por: Hou, Xiao-Xia, et al.
Publicado: (2018)

Mechanisms underlying purinergic P2X3 receptor-mediated mechanical allodynia induced in diabetic rats
por: Xu, Guang-Yin, et al.
Publicado: (2011)

The role of the purinergic P2X(7 )receptor in inflammation
por: Lister, Martin F, et al.
Publicado: (2007)

Impact of Caffeine Consumption on Type 2 Diabetes-Induced Spatial Memory Impairment and Neurochemical Alterations in the Hippocampus
por: Duarte, João M. N., et al.
Publicado: (2019)

Interaction of Purinergic P2X4 and P2X7 Receptor Subunits
por: Schneider, Markus, et al.
Publicado: (2017)

Inhibiting purinergic P2X7 receptors with the antagonist brilliant blue G is neuroprotective in an intranigral lipopolysaccharide animal model of Parkinson's disease
por: Wang, Xin-Hong, et al.
Publicado: (2017)

A Possible Causal Involvement of Neuroinflammatory, Purinergic P2X7 Receptors in Psychiatric Disorders
por: Zhang, Ying, et al.
Publicado: (2022)

Smad7 in the hippocampus contributes to memory impairment in aged mice after anesthesia and surgery
por: Liu, Changliang, et al.
Publicado: (2023)

Electroacupuncture diminishes P2X(2) and P2X(3) purinergic receptor expression in dorsal root ganglia of rats with visceral hypersensitivity★
por: Weng, Zhijun, et al.
Publicado: (2013)

P2X4: A fast and sensitive purinergic receptor
por: Suurväli, Jaanus, et al.
Publicado: (2017)

Mitochondrial Localization and Function of the Purinergic Receptor P2X(7)
por: Kroemer, Guido, et al.
Publicado: (2021)

Purinergic 2X7 receptor is involved in adipogenesis and lipid degradation
por: Li, Jing, et al.
Publicado: (2022)

The P2X7 purinergic receptor in intervertebral disc degeneration
por: Penolazzi, Letizia, et al.
Publicado: (2021)

Electroconvulsive Shock Enhances Responsive Motility and Purinergic Currents in Microglia in the Mouse Hippocampus
por: Sepulveda-Rodriguez, Alberto, et al.
Publicado: (2019)

Development of a Mouse Reporter Strain for the Purinergic P2X(2) Receptor
por: Kim, Seol-Hee, et al.
Publicado: (2020)

The purinergic receptor P2X5 regulates inflammasome activity and hyper-multinucleation of murine osteoclasts
por: Kim, Hyunsoo, et al.
Publicado: (2017)

Purinergic control of inflammation and thrombosis: Role of P2X1 receptors
por: Oury, Cécile, et al.
Publicado: (2014)

Associations Between the Purinergic Receptor P2X7 and Leprosy Disease
por: Souza, Rebeka da Conceição, et al.
Publicado: (2021)

Gestational Exposure to Particulate Matter 2.5 (PM(2.5)) Leads to Spatial Memory Dysfunction and Neurodevelopmental Impairment in Hippocampus of Mice Offspring
por: Zheng, Xinrui, et al.
Publicado: (2019)

Endogenous retroviruses are associated with hippocampus-based memory impairment
por: Sankowski, Roman, et al.
Publicado: (2019)

Methamphetamine Exposure in Adolescent Impairs Memory of Mice in Adulthood Accompanied by Changes in Neuroplasticity in the Dorsal Hippocampus
por: Liang, Min, et al.
Publicado: (2022)

Complement-associated loss of CA2 inhibitory synapses in the demyelinated hippocampus impairs memory
por: Ramaglia, Valeria, et al.
Publicado: (2021)

Understanding the Role of Purinergic P2X7 Receptors in the Gastrointestinal System: A Systematic Review
por: Cheng, Nathalie, et al.
Publicado: (2021)

Rescue of Cyclic AMP Mediated Long Term Potentiation Impairment in the Hippocampus of Mecp2 Knockout (Mecp2(-/y)) Mice by Rolipram
por: Balakrishnan, Saju, et al.
Publicado: (2016)

Lack of the purinergic receptor P2X(7) results in resistance to contact hypersensitivity
por: Weber, Felix C., et al.
Publicado: (2010)

The purinergic receptor P2X5 contributes to bone loss in experimental periodontitis
por: Kim, Hyunsoo, et al.
Publicado: (2018)

Special Issue for Purinergic Receptors, Particularly P2X(7) Receptor, in the Eye
por: Sugiyama, Tetsuya
Publicado: (2018)

Subfailure Overstretch Injury Leads to Reversible Functional Impairment and Purinergic P2X7 Receptor Activation in Intact Vascular Tissue
por: Luo, Weifeng, et al.
Publicado: (2016)

Memory rescue and learning in synaptic impaired neuronal circuits
por: Li, Kwan Tung, et al.
Publicado: (2023)

Adult Stress Promotes Purinergic Signaling to Induce Visceral Pain in Rats with Neonatal Maternal Deprivation
por: Hu, Shufen, et al.
Publicado: (2020)

Using antibodies against P2Y and P2X receptors in purinergic signaling research
por: Brass, Dovrat, et al.
Publicado: (2011)

Opposing Roles of Calcium and Intracellular ATP on Gating of the Purinergic P2X2 Receptor Channel
por: Rokic, Milos B., et al.
Publicado: (2018)

A novel P2X2‐dependent purinergic mechanism of enteric gliosis in intestinal inflammation
por: Schneider, Reiner, et al.
Publicado: (2020)

Overexpression of Indian hedgehog partially rescues short stature homeobox 2-overexpression-associated congenital dysplasia of the temporomandibular joint in mice
por: LI, XIHAI, et al.
Publicado: (2015)

Inhibition of Necroptosis Rescues SAH-Induced Synaptic Impairments in Hippocampus via CREB-BDNF Pathway
por: Yang, Chunlei, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_9uh7vp2nmgnghp8hqsu4o1hm2a