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Altered Energy Metabolism During Early Optic Nerve Crush Injury: Implications of Warburg-Like Aerobic Glycolysis in Facilitating Retinal Ganglion Cell Survival

Neurons, especially axons, are metabolically demanding and energetically vulnerable during injury. However, the exact energy budget alterations that occur early after axon injury and the effects of these changes on neuronal survival remain unknown. Using a classic mouse model of optic nerve-crush in...

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Detalles Bibliográficos
Autores principales: Zhu, Jingyi, Li, Ping, Zhou, Yuan-Guo, Ye, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Singapore 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7340706/
https://www.ncbi.nlm.nih.gov/pubmed/32277382
http://dx.doi.org/10.1007/s12264-020-00490-x