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SOCS3 Attenuates GM-CSF/IFN-γ-Mediated Inflammation During Spontaneous Spinal Cord Regeneration
SOCS3, a feedback inhibitor of the JAK/STAT signal pathway, negatively regulates axonal regrowth and inflammation in the central nervous system (CNS). Here, we demonstrated a distinct role of SOCS3 in the injured spinal cord of the gecko following tail amputation. Severing the gecko spinal cord did...
Autores principales: | Zhang, Xuejie, He, Bingqiang, Li, Hui, Wang, Yingjie, Zhou, Yue, Wang, Wenjuan, Song, Tiancheng, Du, Nan, Gu, Xingxing, Luo, Yi, Wang, Yongjun |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Singapore
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7340708/ https://www.ncbi.nlm.nih.gov/pubmed/32306216 http://dx.doi.org/10.1007/s12264-020-00493-8 |
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