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Treatment of invasive Paget’s disease of the vulva in pregnancy: A case report

• Invasive adenocarcinoma of the vulva arising from extramammary Paget’s disease is possible in women of child-bearing age. • Radical vulvectomy, sentinel lymph node biopsy, and inguinal lymphadenectomy are safe and feasible during pregnancy. • Chemotherapy may be used as adjuvant therapy for vulvar...

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Detalles Bibliográficos
Autores principales: Bruce, Kelly H., Tran, Arthur-Quan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7340971/
https://www.ncbi.nlm.nih.gov/pubmed/32671169
http://dx.doi.org/10.1016/j.gore.2020.100602
Descripción
Sumario:• Invasive adenocarcinoma of the vulva arising from extramammary Paget’s disease is possible in women of child-bearing age. • Radical vulvectomy, sentinel lymph node biopsy, and inguinal lymphadenectomy are safe and feasible during pregnancy. • Chemotherapy may be used as adjuvant therapy for vulvar adenocarcinoma during pregnancy when radiation is contraindicated. • Primary cesarean delivery may be considered for pregnant women with recent vulvar surgery. • Trastuzumab may be considered for maintenance therapy of Her2/Neu positive vulvar cancer in postpartum women.