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Trajectory and Functional Analysis of PD‐1(high) CD4(+)CD8(+) T Cells in Hepatocellular Carcinoma by Single‐Cell Cytometry and Transcriptome Sequencing

The spatial heterogeneity of immune microenvironment in hepatocellular carcinoma (HCC) remains elusive. Here, a single‐cell study involving 17 432 600 immune cells of 39 matched HCC (T), nontumor (N), and leading‐edge (L) specimens by mass cytometry is conducted. The tumor‐associated CD4/CD8 double‐...

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Detalles Bibliográficos
Autores principales:	Zheng, Bo, Wang, Dongfang, Qiu, Xinyao, Luo, Guijuan, Wu, Tong, Yang, Shuai, Li, Zhixuan, Zhu, Yanjing, Wang, Shan, Wu, Rui, Sui, Chengjun, Gu, Ziqi, Shen, Siyun, Jeong, Seogsong, Wu, Xuan, Gu, Jin, Wang, Hongyang, Chen, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2020
Materias:	Full Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341083/ https://www.ncbi.nlm.nih.gov/pubmed/32670760 http://dx.doi.org/10.1002/advs.202000224

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