A Loop‐Based and AGO‐Incorporated Virtual Screening Model Targeting AGO‐Mediated miRNA–mRNA Interactions for Drug Discovery to Rescue Bone Phenotype in Genetically Modified Mice

Several virtual screening models are proposed to screen small molecules only targeting primary miRNAs without selectivity. Few attempts have been made to develop virtual screening strategies for discovering small molecules targeting mature miRNAs. Mature miRNAs and their specific target mRNA can for...

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Detalles Bibliográficos
Autores principales: Zhuo, Zhenjian, Wan, Youyang, Guan, Daogang, Ni, Shuaijian, Wang, Luyao, Zhang, Zongkang, Liu, Jin, Liang, Chao, Yu, Yuanyuan, Lu, Aiping, Zhang, Ge, Zhang, Bao‐Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2020
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341099/
https://www.ncbi.nlm.nih.gov/pubmed/32670749
http://dx.doi.org/10.1002/advs.201903451

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