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The Ancestral Caenorhabditis elegans Cuticle Suppresses rol-1
Genetic background commonly modifies the effects of mutations. We discovered that worms mutant for the canonical rol-1 gene, identified by Brenner in 1974, do not roll in the genetic background of the wild strain CB4856. Using linkage mapping, association analysis and gene editing, we determined tha...
Autores principales: | Noble, Luke M., Miah, Asif, Kaur, Taniya, Rockman, Matthew V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Genetics Society of America
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341120/ https://www.ncbi.nlm.nih.gov/pubmed/32423919 http://dx.doi.org/10.1534/g3.120.401336 |
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