Epidemiologic and histologic characteristics of CNS lesions: a 20-year experience of a tertiary center in Lebanon

AIM: Report the epidemiologic and histologic characteristics of CNS lesions in the Lebanese population. METHODS: We conducted a retrospective study evaluating 2025 CNS lesions diagnosed between 1998 and 2017 in the pathology laboratory of a Lebanese tertiary center. RESULTS: 52.2% of patients were m...

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Detalles Bibliográficos
Autores principales: Eid, Roland, Hage, Stephanie, Antonios, Ingrid, Moussa, Rita, Khoury, Makram, Haddad, Fady Ghassan, Kourie, Hampig Raphael, Kesrouani, Carole, Ghorra, Claude, Abadjian, Gerard, Kattan, Joseph
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2020
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341156/
https://www.ncbi.nlm.nih.gov/pubmed/32603607
http://dx.doi.org/10.2217/cns-2020-0001
Descripción
Sumario:AIM: Report the epidemiologic and histologic characteristics of CNS lesions in the Lebanese population. METHODS: We conducted a retrospective study evaluating 2025 CNS lesions diagnosed between 1998 and 2017 in the pathology laboratory of a Lebanese tertiary center. RESULTS: 52.2% of patients were men with a median age of 50 years. The most frequent symptoms were epilepsy (22.5%), headache (20.6%) and motor impairment (19.9%). 90.7% of tumors were primary. Lung (35.6%) and breast (16.5%) were the most frequent primaries of metastases. 46.2% of primary CNS tumors were glial, predominantly astrocytic (56.4%), and (42.5%) were nonglial, predominantly meningeal tumors (58%). CONCLUSION: Compared with Western literature, the Lebanese population is characterized by a younger age of onset of brain tumors, a lower rate of meningiomas and a higher rate of gliomas.

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