Cargando…

Form of Supplemental Selenium in Vitamin-Mineral Premixes Differentially Affects Early Luteal and Gestational Concentrations of Progesterone, and Postpartum Concentrations of Prolactin in Beef Cows

SIMPLE SUMMARY: Soils with inadequate levels of selenium are widespread in the northwest, northeast, and southeast USA. Therefore, dietary supplementation of forage-grazing beef cattle with additional selenium is recommended in these regions for optimal growth, immune function, and fertility. We hav...

Descripción completa

Detalles Bibliográficos
Autores principales: Carr, Sarah, Jia, Yang, Crites, Benjamin, Hamilton, Charles, Burris, Walter, Edwards, J. Lannett, Matthews, James, Bridges, Phillip J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341279/
https://www.ncbi.nlm.nih.gov/pubmed/32503110
http://dx.doi.org/10.3390/ani10060967
_version_ 1783555203360882688
author Carr, Sarah
Jia, Yang
Crites, Benjamin
Hamilton, Charles
Burris, Walter
Edwards, J. Lannett
Matthews, James
Bridges, Phillip J.
author_facet Carr, Sarah
Jia, Yang
Crites, Benjamin
Hamilton, Charles
Burris, Walter
Edwards, J. Lannett
Matthews, James
Bridges, Phillip J.
author_sort Carr, Sarah
collection PubMed
description SIMPLE SUMMARY: Soils with inadequate levels of selenium are widespread in the northwest, northeast, and southeast USA. Therefore, dietary supplementation of forage-grazing beef cattle with additional selenium is recommended in these regions for optimal growth, immune function, and fertility. We have reported that the form of selenium provided to Angus-cross cows can affect circulating concentrations of progesterone on day 6 of the estrous cycle, a time when increased progesterone is known to promote fertility. Hence, we sought to confirm this initial finding, determine the effect of the form of selenium on peripheral concentrations of progesterone during gestation, and determine the effect of the form of selenium on circulating concentrations of prolactin during lactation. Cows were supplemented with equimolar amounts of either an inorganic form, or a 1:1 mixture of inorganic and organic forms of selenium throughout this study. We confirmed our original finding that the mixed (1:1 inorganic to organic selenium) supplement increased systemic progesterone in the early luteal phase of the estrous cycle, and determined that cows maintained on this same supplement had elevated concentrations of progesterone throughout gestation. Interestingly, these same cows revealed a treatment-induced decrease in systemic prolactin during late lactation. The form of selenium provided to cows can be manipulated to affect reproductive responses and offers a viable management tool to improve fertility in cows in regions with selenium-deficient soils. ABSTRACT: Soils with marginal to deficient levels of selenium (Se) are widespread in the northwest, northeast, and southeast US. Supplementation to the diet of forage-grazing beef cattle with a vitamin-mineral mix containing additional Se is recommended in these geographic regions. We have reported that the form of supplemental Se provided to Angus-cross beef cows can affect circulating levels of progesterone (P4) on day 6 of the estrous cycle, a time when increased P4 is known to promote fertility. The objectives of this study were to (1) confirm and expand upon our initial report that the form of Se provided to cows affects early luteal-phase concentrations of systemic P4, (2) determine the effects of the form of Se on concentrations of P4 during gestation, and (3) determine the effects of the form of Se on concentrations of prolactin (PRL) during lactation. Throughout this study, Angus-cross beef cows had ad libitum access to a vitamin-mineral mix containing 35 ppm of Se in either an inorganic form (ISe) or a 1:1 mix of inorganic and organic forms (MIX). We observed a MIX-induced increase (p = 0.006) in systemic concentrations of P4 on day 7 but not on days 4 or 10 of the estrous cycle, consistent with our earlier report. We observed a MIX-induced increase (p = 0.02) in the systemic concentration of P4 at months 1, 3, 5, and 7 of gestation, and a MIX-induced decrease (p < 0.05) in systemic concentrations of PRL at months 5 and 6 of lactation. In summary, the form of Se provided to cows can be manipulated to affect the early luteal phase and gestational concentrations of P4, and postpartum concentrations of PRL.
format Online
Article
Text
id pubmed-7341279
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher MDPI
record_format MEDLINE/PubMed
spelling pubmed-73412792020-07-14 Form of Supplemental Selenium in Vitamin-Mineral Premixes Differentially Affects Early Luteal and Gestational Concentrations of Progesterone, and Postpartum Concentrations of Prolactin in Beef Cows Carr, Sarah Jia, Yang Crites, Benjamin Hamilton, Charles Burris, Walter Edwards, J. Lannett Matthews, James Bridges, Phillip J. Animals (Basel) Article SIMPLE SUMMARY: Soils with inadequate levels of selenium are widespread in the northwest, northeast, and southeast USA. Therefore, dietary supplementation of forage-grazing beef cattle with additional selenium is recommended in these regions for optimal growth, immune function, and fertility. We have reported that the form of selenium provided to Angus-cross cows can affect circulating concentrations of progesterone on day 6 of the estrous cycle, a time when increased progesterone is known to promote fertility. Hence, we sought to confirm this initial finding, determine the effect of the form of selenium on peripheral concentrations of progesterone during gestation, and determine the effect of the form of selenium on circulating concentrations of prolactin during lactation. Cows were supplemented with equimolar amounts of either an inorganic form, or a 1:1 mixture of inorganic and organic forms of selenium throughout this study. We confirmed our original finding that the mixed (1:1 inorganic to organic selenium) supplement increased systemic progesterone in the early luteal phase of the estrous cycle, and determined that cows maintained on this same supplement had elevated concentrations of progesterone throughout gestation. Interestingly, these same cows revealed a treatment-induced decrease in systemic prolactin during late lactation. The form of selenium provided to cows can be manipulated to affect reproductive responses and offers a viable management tool to improve fertility in cows in regions with selenium-deficient soils. ABSTRACT: Soils with marginal to deficient levels of selenium (Se) are widespread in the northwest, northeast, and southeast US. Supplementation to the diet of forage-grazing beef cattle with a vitamin-mineral mix containing additional Se is recommended in these geographic regions. We have reported that the form of supplemental Se provided to Angus-cross beef cows can affect circulating levels of progesterone (P4) on day 6 of the estrous cycle, a time when increased P4 is known to promote fertility. The objectives of this study were to (1) confirm and expand upon our initial report that the form of Se provided to cows affects early luteal-phase concentrations of systemic P4, (2) determine the effects of the form of Se on concentrations of P4 during gestation, and (3) determine the effects of the form of Se on concentrations of prolactin (PRL) during lactation. Throughout this study, Angus-cross beef cows had ad libitum access to a vitamin-mineral mix containing 35 ppm of Se in either an inorganic form (ISe) or a 1:1 mix of inorganic and organic forms (MIX). We observed a MIX-induced increase (p = 0.006) in systemic concentrations of P4 on day 7 but not on days 4 or 10 of the estrous cycle, consistent with our earlier report. We observed a MIX-induced increase (p = 0.02) in the systemic concentration of P4 at months 1, 3, 5, and 7 of gestation, and a MIX-induced decrease (p < 0.05) in systemic concentrations of PRL at months 5 and 6 of lactation. In summary, the form of Se provided to cows can be manipulated to affect the early luteal phase and gestational concentrations of P4, and postpartum concentrations of PRL. MDPI 2020-06-03 /pmc/articles/PMC7341279/ /pubmed/32503110 http://dx.doi.org/10.3390/ani10060967 Text en © 2020 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Article
Carr, Sarah
Jia, Yang
Crites, Benjamin
Hamilton, Charles
Burris, Walter
Edwards, J. Lannett
Matthews, James
Bridges, Phillip J.
Form of Supplemental Selenium in Vitamin-Mineral Premixes Differentially Affects Early Luteal and Gestational Concentrations of Progesterone, and Postpartum Concentrations of Prolactin in Beef Cows
title Form of Supplemental Selenium in Vitamin-Mineral Premixes Differentially Affects Early Luteal and Gestational Concentrations of Progesterone, and Postpartum Concentrations of Prolactin in Beef Cows
title_full Form of Supplemental Selenium in Vitamin-Mineral Premixes Differentially Affects Early Luteal and Gestational Concentrations of Progesterone, and Postpartum Concentrations of Prolactin in Beef Cows
title_fullStr Form of Supplemental Selenium in Vitamin-Mineral Premixes Differentially Affects Early Luteal and Gestational Concentrations of Progesterone, and Postpartum Concentrations of Prolactin in Beef Cows
title_full_unstemmed Form of Supplemental Selenium in Vitamin-Mineral Premixes Differentially Affects Early Luteal and Gestational Concentrations of Progesterone, and Postpartum Concentrations of Prolactin in Beef Cows
title_short Form of Supplemental Selenium in Vitamin-Mineral Premixes Differentially Affects Early Luteal and Gestational Concentrations of Progesterone, and Postpartum Concentrations of Prolactin in Beef Cows
title_sort form of supplemental selenium in vitamin-mineral premixes differentially affects early luteal and gestational concentrations of progesterone, and postpartum concentrations of prolactin in beef cows
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341279/
https://www.ncbi.nlm.nih.gov/pubmed/32503110
http://dx.doi.org/10.3390/ani10060967
work_keys_str_mv AT carrsarah formofsupplementalseleniuminvitaminmineralpremixesdifferentiallyaffectsearlylutealandgestationalconcentrationsofprogesteroneandpostpartumconcentrationsofprolactininbeefcows
AT jiayang formofsupplementalseleniuminvitaminmineralpremixesdifferentiallyaffectsearlylutealandgestationalconcentrationsofprogesteroneandpostpartumconcentrationsofprolactininbeefcows
AT critesbenjamin formofsupplementalseleniuminvitaminmineralpremixesdifferentiallyaffectsearlylutealandgestationalconcentrationsofprogesteroneandpostpartumconcentrationsofprolactininbeefcows
AT hamiltoncharles formofsupplementalseleniuminvitaminmineralpremixesdifferentiallyaffectsearlylutealandgestationalconcentrationsofprogesteroneandpostpartumconcentrationsofprolactininbeefcows
AT burriswalter formofsupplementalseleniuminvitaminmineralpremixesdifferentiallyaffectsearlylutealandgestationalconcentrationsofprogesteroneandpostpartumconcentrationsofprolactininbeefcows
AT edwardsjlannett formofsupplementalseleniuminvitaminmineralpremixesdifferentiallyaffectsearlylutealandgestationalconcentrationsofprogesteroneandpostpartumconcentrationsofprolactininbeefcows
AT matthewsjames formofsupplementalseleniuminvitaminmineralpremixesdifferentiallyaffectsearlylutealandgestationalconcentrationsofprogesteroneandpostpartumconcentrationsofprolactininbeefcows
AT bridgesphillipj formofsupplementalseleniuminvitaminmineralpremixesdifferentiallyaffectsearlylutealandgestationalconcentrationsofprogesteroneandpostpartumconcentrationsofprolactininbeefcows