Evaluation of Sugarcane-Derived Polyphenols on the Pre-Weaning and Post-Weaning Growth of Gilt Progeny

SIMPLE SUMMARY: Gilt progeny are characterised by their poor lifetime growth performance compared with sow progeny. Various feeding strategies that employ the use of additives may be used to improve their growth. Gilts are said to be in increased oxidative stress throughout lactation, which may contribute to the reduced growth performance seen in their progeny. Furthermore, weaning is associated with increased inflammation, which can reduce growth after weaning. In this study, both late gestation/lactation diets and weaner diets were supplemented with a sugarcane extract rich in polyphenols owing to their anti-oxidative and anti-inflammatory properties to collectively improve the growth of gilt progeny. However, no improvements of growth performance of gilt progeny in both the pre-weaning and post-weaning periods were observed in response to polyphenol supplementation and sow progeny continuously outperformed gilt progeny. Furthermore, when inflammation was measured using the inflammatory cytokine interleukin-1β, no differences were found between the control and polyphenol supplemented group. However, gilt progeny exhibited reduced circulating interleukin-1β overall. In summary, gilt progeny experience persistent underperformance that may be coupled in part to poorer immune development and polyphenol supplementation did not overcome the persistent underperformance. ABSTRACT: Gilt progeny (GP) exhibit poorer growth compared with sow progeny (SP), particularly in the pre-weaning and post-weaning period. Late gestation/lactation sow diets and weaner diets were supplemented with 0.5% Polygain (POL), a sugarcane extract rich in polyphenols, to collectively improve GP growth in these periods. Gilts (n = 60) and sows (n = 68, parities 2 and 3) were fed a control or POL diet. Weaned GP (n = 79) and SP (n = 92) born to these dams were also fed either a CON or POL diet. Gilts litters weighed less than sow litters at birth and 21 days (p < 0.001 for both) and were not improved by POL (p = 0.80 and 0.54, respectively). GP were lighter than SP at day 7 and day 14 post-weaning (p < 0.001 for both) and were not improved by the POL diet at these timepoints (p = 0.61 and 0.97, respectively). Plasma interleukin-1β (IL-1β) was increased at weaning despite POL supplementation (p = 0.022) and GP had reduced IL-1β overall (p = 0.021). Overall, POL was unable to improve growth in GP and the attenuated immune response seen in GP could be contributing to their poor growth performance.