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Lipid Compositions in Infant Formulas Affect the Solubilization of Antimalarial Drugs Artefenomel (OZ439) and Ferroquine during Digestion

[Image: see text] Recent studies have shown that the solubilization of two antimalarial drug candidates, artefenomel (OZ439) and ferroquine (FQ), designed to provide a single-dose combination therapy for uncomplicated malaria can be enhanced using milk as a lipid-based formulation. However, milk as...

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Detalles Bibliográficos
Autores principales:	Salim, Malinda, Ramirez, Gisela, Peng, Kang-Yu, Clulow, Andrew J., Hawley, Adrian, Ramachandruni, Hanu, Beilles, Stephane, Boyd, Ben J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2020
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341521/ https://www.ncbi.nlm.nih.gov/pubmed/32574056 http://dx.doi.org/10.1021/acs.molpharmaceut.0c00475

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