The diabetic microenvironment causes mitochondrial oxidative stress in glomerular endothelial cells and pathological crosstalk with podocytes

BACKGROUND: In the setting of diabetes mellitus, mitochondrial dysfunction and oxidative stress are important pathogenic mechanisms causing end organ damage, including diabetic kidney disease (DKD), but mechanistic understanding at a cellular level remains obscure. In mouse models of DKD, glomerular...

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Detalles Bibliográficos
Autores principales: Casalena, Gabriella A., Yu, Liping, Gil, Roberto, Rodriguez, Samuel, Sosa, Shantel, Janssen, William, Azeloglu, Evren U., Leventhal, Jeremy S., Daehn, Ilse S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341607/
https://www.ncbi.nlm.nih.gov/pubmed/32641054
http://dx.doi.org/10.1186/s12964-020-00605-x

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