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The natural alkaloid Jerantinine B has activity in acute myeloid leukemia cells through a mechanism involving c-Jun

BACKGROUND: Acute myeloid leukemia (AML) is a heterogenous hematological malignancy with poor long-term survival. New drugs which improve the outcome of AML patients are urgently required. In this work, the activity and mechanism of action of the cytotoxic indole alkaloid Jerantinine B (JB), was exa...

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Detalles Bibliográficos
Autores principales:	Alhuthali, Hayaa Moeed, Bradshaw, Tracey D., Lim, Kuan-Hon, Kam, Toh-Seok, Seedhouse, Claire H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2020
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341637/ https://www.ncbi.nlm.nih.gov/pubmed/32635894 http://dx.doi.org/10.1186/s12885-020-07119-2

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