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Stress-induced NLRP3 inflammasome activation negatively regulates fear memory in mice

BACKGROUND: Persistent inflammation dysregulation and cognitive decline have been associated with several trauma- and stress-related disorders such as posttraumatic stress disorder (PTSD) and anxiety disorder. Despite the abundant discoveries of neuroinflammation in such disorders, the underlying me...

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Detalles Bibliográficos
Autores principales: Dong, Yuan, Li, Shuoshuo, Lu, Yiming, Li, Xiaoheng, Liao, Yajin, Peng, Zhixin, Li, Yunfeng, Hou, Lin, Yuan, Zengqiang, Cheng, Jinbo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341659/
https://www.ncbi.nlm.nih.gov/pubmed/32635937
http://dx.doi.org/10.1186/s12974-020-01842-0

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