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Sodium ions allosterically modulate the M2 muscarinic receptor

G protein coupled receptors (GPCRs) play a key role in the vast majority of cellular signal transduction processes. Previous experimental evidence has shown that sodium ion (Na(+)) allosterically modulate several class A GPCRs and theoretical studies suggested that the same also holds true for musca...

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Detalles Bibliográficos
Autores principales:	Friedman, Sheli, Tauber, Merav, Ben-Chaim, Yair
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341750/ https://www.ncbi.nlm.nih.gov/pubmed/32636499 http://dx.doi.org/10.1038/s41598-020-68133-9

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