Sequential serological surveys in the early stages of the coronavirus disease epidemic: limitations and perspectives

INTRODUCTION: Estimates of the number of individuals infected by severe acute respiratory syndrome coronavirus 2 are important for health planning and establishment of expectations regarding herd immunity. METHODS: Seven testing rounds of a serological survey were conducted at 1-week intervals betwe...

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Detalles Bibliográficos
Autores principales: Vieira, Marcelo Adriano da Cunha e Silva, Vieira, Chrystiany Plácido de Brito, Borba, Amaríles de Souza, Melo, Maria Clara de Carvalho, Oliveira, Marilene de Sousa, Melo, Rodrigo Moraes, Nunes, Vanessa Veloso, Santana, Wesllany Sousa, de Aguiar, Yara Amorim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Medicina Tropical - SBMT 2020
Materias:
Short Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341829/
https://www.ncbi.nlm.nih.gov/pubmed/32638891
http://dx.doi.org/10.1590/0037-8682-0351-2020
Descripción
Sumario:INTRODUCTION: Estimates of the number of individuals infected by severe acute respiratory syndrome coronavirus 2 are important for health planning and establishment of expectations regarding herd immunity. METHODS: Seven testing rounds of a serological survey were conducted at 1-week intervals between April 19 and May 31, 2020 in Teresina municipality. RESULTS: Over the 7 weeks, serological positivity increased from 0.56% (95% confidence interval [CI]: 0.18%-1.30%) to 8.33% (95% CI: 6.61%-10.33%), representing 33-53 persons infected for each reported case. CONCLUSIONS: Serological screening may be an important tool for understanding the immunity of a population and planning community interventions.

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