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Confirmed Invasive Pulmonary Aspergillosis and COVID-19: the value of postmortem findings to support antemortem management
We present postmortem evidence of invasive pulmonary aspergillosis (IPA) in a patient with severe COVID-19. Autopsies of COVID-19 confirmed cases were performed. The patient died despite antimicrobials, mechanical ventilation, and vasopressor support. Histopathology and peripheral blood galactomanna...
| Autores principales: | , , , , , , , , , , , , , , , , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Sociedade Brasileira de Medicina Tropical - SBMT
2020
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341831/ https://www.ncbi.nlm.nih.gov/pubmed/32638890 http://dx.doi.org/10.1590/0037-8682-0401-2020 |
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| author | Santana, Monique Freire Pivoto, Guilherme Alexandre, Márcia A. Araujo Baía-da-Silva, Djane Clarys Borba, Mayla Gabriela da Silva Val, Fernando Almeida Brito-Sousa, Jose Diego Melo, Gisely Cardoso Monteiro, Wuelton Marcelo Souza, João Vicente Braga Pinheiro, Silviane Bezerra Ferreira, Luiz Carlos Lima Naveca, Felipe Gomes Nascimento, Valdinete Alves Corado, André Lima Guerra Hajjar, Ludhmila Abrahão Silva, João Ricardo Siva, George Alan Villarouco Pasqualotto, Alessandro C. Lacerda, Marcus Vinícius Guimarães |
| author_facet | Santana, Monique Freire Pivoto, Guilherme Alexandre, Márcia A. Araujo Baía-da-Silva, Djane Clarys Borba, Mayla Gabriela da Silva Val, Fernando Almeida Brito-Sousa, Jose Diego Melo, Gisely Cardoso Monteiro, Wuelton Marcelo Souza, João Vicente Braga Pinheiro, Silviane Bezerra Ferreira, Luiz Carlos Lima Naveca, Felipe Gomes Nascimento, Valdinete Alves Corado, André Lima Guerra Hajjar, Ludhmila Abrahão Silva, João Ricardo Siva, George Alan Villarouco Pasqualotto, Alessandro C. Lacerda, Marcus Vinícius Guimarães |
| author_sort | Santana, Monique Freire |
| collection | PubMed |
| description | We present postmortem evidence of invasive pulmonary aspergillosis (IPA) in a patient with severe COVID-19. Autopsies of COVID-19 confirmed cases were performed. The patient died despite antimicrobials, mechanical ventilation, and vasopressor support. Histopathology and peripheral blood galactomannan antigen testing confirmed IPA. Aspergillus penicillioides infection was confirmed by nucleotide sequencing and BLAST analysis. Further reports are needed to assess the occurrence and frequency of IPA in SARS-CoV-2 infections, and how they interact clinically. |
| format | Online Article Text |
| id | pubmed-7341831 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2020 |
| publisher | Sociedade Brasileira de Medicina Tropical - SBMT |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-73418312020-07-10 Confirmed Invasive Pulmonary Aspergillosis and COVID-19: the value of postmortem findings to support antemortem management Santana, Monique Freire Pivoto, Guilherme Alexandre, Márcia A. Araujo Baía-da-Silva, Djane Clarys Borba, Mayla Gabriela da Silva Val, Fernando Almeida Brito-Sousa, Jose Diego Melo, Gisely Cardoso Monteiro, Wuelton Marcelo Souza, João Vicente Braga Pinheiro, Silviane Bezerra Ferreira, Luiz Carlos Lima Naveca, Felipe Gomes Nascimento, Valdinete Alves Corado, André Lima Guerra Hajjar, Ludhmila Abrahão Silva, João Ricardo Siva, George Alan Villarouco Pasqualotto, Alessandro C. Lacerda, Marcus Vinícius Guimarães Rev Soc Bras Med Trop Case Report We present postmortem evidence of invasive pulmonary aspergillosis (IPA) in a patient with severe COVID-19. Autopsies of COVID-19 confirmed cases were performed. The patient died despite antimicrobials, mechanical ventilation, and vasopressor support. Histopathology and peripheral blood galactomannan antigen testing confirmed IPA. Aspergillus penicillioides infection was confirmed by nucleotide sequencing and BLAST analysis. Further reports are needed to assess the occurrence and frequency of IPA in SARS-CoV-2 infections, and how they interact clinically. Sociedade Brasileira de Medicina Tropical - SBMT 2020-07-03 /pmc/articles/PMC7341831/ /pubmed/32638890 http://dx.doi.org/10.1590/0037-8682-0401-2020 Text en https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License |
| spellingShingle | Case Report Santana, Monique Freire Pivoto, Guilherme Alexandre, Márcia A. Araujo Baía-da-Silva, Djane Clarys Borba, Mayla Gabriela da Silva Val, Fernando Almeida Brito-Sousa, Jose Diego Melo, Gisely Cardoso Monteiro, Wuelton Marcelo Souza, João Vicente Braga Pinheiro, Silviane Bezerra Ferreira, Luiz Carlos Lima Naveca, Felipe Gomes Nascimento, Valdinete Alves Corado, André Lima Guerra Hajjar, Ludhmila Abrahão Silva, João Ricardo Siva, George Alan Villarouco Pasqualotto, Alessandro C. Lacerda, Marcus Vinícius Guimarães Confirmed Invasive Pulmonary Aspergillosis and COVID-19: the value of postmortem findings to support antemortem management |
| title | Confirmed Invasive Pulmonary Aspergillosis and COVID-19: the value of postmortem findings to support antemortem management |
| title_full | Confirmed Invasive Pulmonary Aspergillosis and COVID-19: the value of postmortem findings to support antemortem management |
| title_fullStr | Confirmed Invasive Pulmonary Aspergillosis and COVID-19: the value of postmortem findings to support antemortem management |
| title_full_unstemmed | Confirmed Invasive Pulmonary Aspergillosis and COVID-19: the value of postmortem findings to support antemortem management |
| title_short | Confirmed Invasive Pulmonary Aspergillosis and COVID-19: the value of postmortem findings to support antemortem management |
| title_sort | confirmed invasive pulmonary aspergillosis and covid-19: the value of postmortem findings to support antemortem management |
| topic | Case Report |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341831/ https://www.ncbi.nlm.nih.gov/pubmed/32638890 http://dx.doi.org/10.1590/0037-8682-0401-2020 |
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