Cargando…

Exercise tests in Chagas cardiomyopathy: an overview of functional evaluation, prognostic significance, and current challenges

Patients with Chagas cardiomyopathy (ChC) usually progress with fatigue and dyspnea. Exercise tests are valuable for the functional evaluation of these patients. However, information about the applicability of the exercise tests is scattered, and no studies have systematically reviewed the results....

Descripción completa

Detalles Bibliográficos
Autores principales: Costa, Henrique Silveira, Lima, Márcia Maria Oliveira, Figueiredo, Pedro Henrique Scheidt, Lima, Vanessa Pereira, Ávila, Matheus Ribeiro, de Menezes, Kenia Kiefer Parreiras, Mendonça, Vanessa Amaral, Lacerda, Ana Cristina Rodrigues, Nunes, Maria Carmo Pereira, Mediano, Mauro Felippe Felix, Rocha, Manoel Otávio da Costa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Medicina Tropical - SBMT 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341832/
https://www.ncbi.nlm.nih.gov/pubmed/32638887
http://dx.doi.org/10.1590/0037-8682-0100-2020
_version_ 1783555314485821440
author Costa, Henrique Silveira
Lima, Márcia Maria Oliveira
Figueiredo, Pedro Henrique Scheidt
Lima, Vanessa Pereira
Ávila, Matheus Ribeiro
de Menezes, Kenia Kiefer Parreiras
Mendonça, Vanessa Amaral
Lacerda, Ana Cristina Rodrigues
Nunes, Maria Carmo Pereira
Mediano, Mauro Felippe Felix
Rocha, Manoel Otávio da Costa
author_facet Costa, Henrique Silveira
Lima, Márcia Maria Oliveira
Figueiredo, Pedro Henrique Scheidt
Lima, Vanessa Pereira
Ávila, Matheus Ribeiro
de Menezes, Kenia Kiefer Parreiras
Mendonça, Vanessa Amaral
Lacerda, Ana Cristina Rodrigues
Nunes, Maria Carmo Pereira
Mediano, Mauro Felippe Felix
Rocha, Manoel Otávio da Costa
author_sort Costa, Henrique Silveira
collection PubMed
description Patients with Chagas cardiomyopathy (ChC) usually progress with fatigue and dyspnea. Exercise tests are valuable for the functional evaluation of these patients. However, information about the applicability of the exercise tests is scattered, and no studies have systematically reviewed the results. Thus, the present review explored the general aspects and prognostic value of exercise tests in patients with ChC. A literature search of the MEDLINE, Web of Science, CINAHL, Scopus, and LILACS databases was performed to identify relevant studies. There were no data restrictions, and articles that met the objective of the study were selected. Articles written in English, Portuguese, and Spanish were considered, and 25 articles were finally included. The peak oxygen uptake (VO2peak) was correlated with demographic and echocardiographic variables. Echocardiographic features of the left ventricular diastolic function and right ventricular systolic function appeared to be determinants of functional capacity, in addition to age and sex. VO2peak was associated with higher mortality, especially in patients with dilated ChC. The minute ventilation/carbon dioxide production slope (VE/VCO2 slope) was a strong predictor of survival; however, more studies are needed to verify this observation. Field tests showed moderate to strong correlation with VO2peak and thus may be inexpensive tools for the functional evaluation of patients with ChC. However, few studies have verified their prognostic significance. While exercise tests are useful tools for functional assessment, information is scarce regarding further considerations, and many of the criteria are based on guidelines for other heart diseases.
format Online
Article
Text
id pubmed-7341832
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher Sociedade Brasileira de Medicina Tropical - SBMT
record_format MEDLINE/PubMed
spelling pubmed-73418322020-07-10 Exercise tests in Chagas cardiomyopathy: an overview of functional evaluation, prognostic significance, and current challenges Costa, Henrique Silveira Lima, Márcia Maria Oliveira Figueiredo, Pedro Henrique Scheidt Lima, Vanessa Pereira Ávila, Matheus Ribeiro de Menezes, Kenia Kiefer Parreiras Mendonça, Vanessa Amaral Lacerda, Ana Cristina Rodrigues Nunes, Maria Carmo Pereira Mediano, Mauro Felippe Felix Rocha, Manoel Otávio da Costa Rev Soc Bras Med Trop Review Article Patients with Chagas cardiomyopathy (ChC) usually progress with fatigue and dyspnea. Exercise tests are valuable for the functional evaluation of these patients. However, information about the applicability of the exercise tests is scattered, and no studies have systematically reviewed the results. Thus, the present review explored the general aspects and prognostic value of exercise tests in patients with ChC. A literature search of the MEDLINE, Web of Science, CINAHL, Scopus, and LILACS databases was performed to identify relevant studies. There were no data restrictions, and articles that met the objective of the study were selected. Articles written in English, Portuguese, and Spanish were considered, and 25 articles were finally included. The peak oxygen uptake (VO2peak) was correlated with demographic and echocardiographic variables. Echocardiographic features of the left ventricular diastolic function and right ventricular systolic function appeared to be determinants of functional capacity, in addition to age and sex. VO2peak was associated with higher mortality, especially in patients with dilated ChC. The minute ventilation/carbon dioxide production slope (VE/VCO2 slope) was a strong predictor of survival; however, more studies are needed to verify this observation. Field tests showed moderate to strong correlation with VO2peak and thus may be inexpensive tools for the functional evaluation of patients with ChC. However, few studies have verified their prognostic significance. While exercise tests are useful tools for functional assessment, information is scarce regarding further considerations, and many of the criteria are based on guidelines for other heart diseases. Sociedade Brasileira de Medicina Tropical - SBMT 2020-07-03 /pmc/articles/PMC7341832/ /pubmed/32638887 http://dx.doi.org/10.1590/0037-8682-0100-2020 Text en https://creativecommons.org/licenses/by/4.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License
spellingShingle Review Article
Costa, Henrique Silveira
Lima, Márcia Maria Oliveira
Figueiredo, Pedro Henrique Scheidt
Lima, Vanessa Pereira
Ávila, Matheus Ribeiro
de Menezes, Kenia Kiefer Parreiras
Mendonça, Vanessa Amaral
Lacerda, Ana Cristina Rodrigues
Nunes, Maria Carmo Pereira
Mediano, Mauro Felippe Felix
Rocha, Manoel Otávio da Costa
Exercise tests in Chagas cardiomyopathy: an overview of functional evaluation, prognostic significance, and current challenges
title Exercise tests in Chagas cardiomyopathy: an overview of functional evaluation, prognostic significance, and current challenges
title_full Exercise tests in Chagas cardiomyopathy: an overview of functional evaluation, prognostic significance, and current challenges
title_fullStr Exercise tests in Chagas cardiomyopathy: an overview of functional evaluation, prognostic significance, and current challenges
title_full_unstemmed Exercise tests in Chagas cardiomyopathy: an overview of functional evaluation, prognostic significance, and current challenges
title_short Exercise tests in Chagas cardiomyopathy: an overview of functional evaluation, prognostic significance, and current challenges
title_sort exercise tests in chagas cardiomyopathy: an overview of functional evaluation, prognostic significance, and current challenges
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341832/
https://www.ncbi.nlm.nih.gov/pubmed/32638887
http://dx.doi.org/10.1590/0037-8682-0100-2020
work_keys_str_mv AT costahenriquesilveira exercisetestsinchagascardiomyopathyanoverviewoffunctionalevaluationprognosticsignificanceandcurrentchallenges
AT limamarciamariaoliveira exercisetestsinchagascardiomyopathyanoverviewoffunctionalevaluationprognosticsignificanceandcurrentchallenges
AT figueiredopedrohenriquescheidt exercisetestsinchagascardiomyopathyanoverviewoffunctionalevaluationprognosticsignificanceandcurrentchallenges
AT limavanessapereira exercisetestsinchagascardiomyopathyanoverviewoffunctionalevaluationprognosticsignificanceandcurrentchallenges
AT avilamatheusribeiro exercisetestsinchagascardiomyopathyanoverviewoffunctionalevaluationprognosticsignificanceandcurrentchallenges
AT demenezeskeniakieferparreiras exercisetestsinchagascardiomyopathyanoverviewoffunctionalevaluationprognosticsignificanceandcurrentchallenges
AT mendoncavanessaamaral exercisetestsinchagascardiomyopathyanoverviewoffunctionalevaluationprognosticsignificanceandcurrentchallenges
AT lacerdaanacristinarodrigues exercisetestsinchagascardiomyopathyanoverviewoffunctionalevaluationprognosticsignificanceandcurrentchallenges
AT nunesmariacarmopereira exercisetestsinchagascardiomyopathyanoverviewoffunctionalevaluationprognosticsignificanceandcurrentchallenges
AT medianomaurofelippefelix exercisetestsinchagascardiomyopathyanoverviewoffunctionalevaluationprognosticsignificanceandcurrentchallenges
AT rochamanoelotaviodacosta exercisetestsinchagascardiomyopathyanoverviewoffunctionalevaluationprognosticsignificanceandcurrentchallenges