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Blocking C-Raf alleviated high-dose small-volume radiation-induced epithelial mesenchymal transition in mice lung

The goal of this study was to develop a potential druggable target for lung injury after SABR through the small animal model. Utilising the model, a radiation dose of 70 Gy or 90 Gy was focally (small volume) delivered to the left lung of mice. The highly expressed phosphorylation form of C-Raf was...

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Detalles Bibliográficos
Autores principales: Hong, Zhen-Yu, Li, Sanke, Liu, Xiaomei, Leng, Xiao-Min, Miao, Zhanhui, Kang, Xiaohong, Niu, Hongrui, Gao, Ming-Qing, Lu, Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341876/
https://www.ncbi.nlm.nih.gov/pubmed/32636458
http://dx.doi.org/10.1038/s41598-020-68175-z