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Blocking C-Raf alleviated high-dose small-volume radiation-induced epithelial mesenchymal transition in mice lung
The goal of this study was to develop a potential druggable target for lung injury after SABR through the small animal model. Utilising the model, a radiation dose of 70 Gy or 90 Gy was focally (small volume) delivered to the left lung of mice. The highly expressed phosphorylation form of C-Raf was...
Autores principales: | Hong, Zhen-Yu, Li, Sanke, Liu, Xiaomei, Leng, Xiao-Min, Miao, Zhanhui, Kang, Xiaohong, Niu, Hongrui, Gao, Ming-Qing, Lu, Ping |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341876/ https://www.ncbi.nlm.nih.gov/pubmed/32636458 http://dx.doi.org/10.1038/s41598-020-68175-z |
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