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Prostaglandin E2 breaks down pericyte–endothelial cell interaction via EP1 and EP4-dependent downregulation of pericyte N-cadherin, connexin-43, and R-Ras

A close association between pericytes and endothelial cells (ECs) is crucial to the stability and function of capillary blood vessels and microvessels. The loss or dysfunction of pericytes results in significant disruption of these blood vessels as observed in pathological conditions, including canc...

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Detalles Bibliográficos
Autores principales: Perrot, Carole Y., Herrera, Jose L., Fournier-Goss, Ashley E., Komatsu, Masanobu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341885/
https://www.ncbi.nlm.nih.gov/pubmed/32636414
http://dx.doi.org/10.1038/s41598-020-68019-w