Cargando…

11β hydroxysteroid dehydrogenase 1: a new marker for predicting response to immune-checkpoint blockade therapy in non-small-cell lung carcinoma

BACKGROUND: Understanding the status of intratumoural immune microenvironment is necessary to ensure the efficacy of immune-checkpoint (IC) blockade therapy. Cortisol plays pivotal roles in glucocorticoid interactions in the immune system. We examined the correlation between intratumourally synthesi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Saito, Ryoko, Miki, Yasuhiro, Abe, Takuto, Miyauchi, Eisaku, Abe, Jiro, Nanamiya, Ren, Inoue, Chihiro, Sato, Ikuro, Sasano, Hironobu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2020
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC7341889/ https://www.ncbi.nlm.nih.gov/pubmed/32336752 http://dx.doi.org/10.1038/s41416-020-0837-3

Ejemplares similares

EphB4 as a Novel Target for the EGFR-Independent Suppressive Effects of Osimertinib on Cell Cycle Progression in Non-Small Cell Lung Cancer
por: Nanamiya, Ren, et al.
Publicado: (2021)

The correlation of p22(phox) and chemosensitivity in EGFR-TKI resistant lung adenocarcinoma
por: Kobayashi, Masayuki, et al.
Publicado: (2019)

PD-L1 Induction by Cancer-Associated Fibroblast-Derived Factors in Lung Adenocarcinoma Cells
por: Inoue, Chihiro, et al.
Publicado: (2019)

Suppression of tumor immune microenvironment via microRNA‐1 after epidermal growth factor receptor‐tyrosine kinase inhibitor resistance acquirement in lung adenocarcinoma
por: Kawana, Sachiko, et al.
Publicado: (2020)

Intratumoral localization and activity of 17β-hydroxysteroid dehydrogenase type 1 in non-small cell lung cancer: a potent prognostic factor
por: Verma, Mohit K, et al.
Publicado: (2013)

11β-Hydroxysteroid Dehydrogenase 2 in Preeclampsia
por: Kosicka, Katarzyna, et al.
Publicado: (2016)

11β-Hydroxysteroid Dehydrogenases and Hypertension in the Metabolic Syndrome
por: Bailey, Matthew A.
Publicado: (2017)

The Significance of MMP-1 in EGFR-TKI–Resistant Lung Adenocarcinoma: Potential for Therapeutic Targeting
por: Saito, Ryoko, et al.
Publicado: (2018)

The increased ratio of 11β-hydroxysteroid dehydrogenase type 1 versus 11β-hydroxysteroid dehydrogenase type 2 in chronic periodontitis irrespective of obesity
por: Nakata, Takaya, et al.
Publicado: (2016)

Idiopathic intracranial hypertension, hormones, and 11β-hydroxysteroid dehydrogenases
por: Markey, Keira A, et al.
Publicado: (2016)

Cortisol, Hypertension and Obesity: The Role of 11β-Hydroxysteroid Dehydrogenase
por: Stewart, Paul M
Publicado: (1998)

17β-Hydroxysteroid Dehydrogenase Type 2 Expression Is Induced by Androgen Signaling in Endometrial Cancer
por: Hashimoto, Chiaki, et al.
Publicado: (2018)

Microbial Hydroxysteroid Dehydrogenases: From Alpha to Omega
por: Doden, Heidi L., et al.
Publicado: (2021)

Effect of Luteolin on 11Beta-Hydroxysteroid Dehydrogenase in Rat Liver and Kidney
por: Tang, Lei, et al.
Publicado: (2015)

Diethylstilbestrol inhibits human and rat 11β-hydroxysteroid dehydrogenase 2
por: Wang, Yiyan, et al.
Publicado: (2019)

Aromatase in human liver and its diseases
por: Hata, Shuko, et al.
Publicado: (2013)

Luteal 3beta-hydroxysteroid dehydrogenase and 20alpha-hydroxysteroid dehydrogenase activities in the rat corpus luteum of pseudopregnancy: Effect of the deciduoma reaction
por: Clementi, Marisa A, et al.
Publicado: (2004)

SUN-742 Roles of Progesterone Receptor Isoform B in Non-Small Cell Lung Cancer Tumor Progression
por: Asavasupreechar, Teeranut, et al.
Publicado: (2020)

17 β -Hydroxysteroid dehydrogenase type 1 and type 2 in human breast carcinoma: a correlation to clinicopathological parameters
por: Suzuki, T, et al.
Publicado: (2000)

Modulation of 11β-Hydroxysteroid Dehydrogenase as a Strategy to Reduce Vascular Inflammation
por: Hadoke, Patrick W. F., et al.
Publicado: (2013)

Effect of Eclipta prostrata on 11Beta-Hydroxysteroid Dehydrogenase in Rat Liver and Kidney
por: Xu, Chenshu, et al.
Publicado: (2014)

Zearalenone Inhibits Rat and Human 11β-Hydroxysteroid Dehydrogenase Type 2
por: Li, Linxi, et al.
Publicado: (2015)

Changes in 11β-Hydroxysteroid Dehydrogenase and Glucocorticoid Receptor Expression in Kawasaki Disease
por: Wang, Juanli, et al.
Publicado: (2017)

Role of 11β-hydroxysteroid dehydrogenase type 1 in the development of atopic dermatitis
por: Lee, Noo Ri, et al.
Publicado: (2020)

11β-Hydroxysteroid dehydrogenases and the brain: From zero to hero, a decade of progress
por: Wyrwoll, Caitlin S., et al.
Publicado: (2011)

Patterning in Placental 11-B Hydroxysteroid Dehydrogenase Methylation According to Prenatal Socioeconomic Adversity
por: Appleton, Allison A., et al.
Publicado: (2013)

The expression of 11β-hydroxysteroid dehydrogenase type 1 is increased in experimental periodontitis in rats
por: Nakata, Takaya, et al.
Publicado: (2016)

Application of ELISA Technique and Human Microsomes in the Search for 11β-Hydroxysteroid Dehydrogenase Inhibitors
por: Kupczyk, Daria, et al.
Publicado: (2019)

Influence of labor on direct and indirect determinants of placental 11beta-hydroxysteroid dehydrogenase activity
por: Huebner, Hanna, et al.
Publicado: (2020)

Adrenal morphology and hydroxysteroid dehydrogenase enzymes in normal and intersex goats
por: Basrur, Parvathi K, et al.
Publicado: (1969)

Posaconazole-Induced Hypertension Due to Inhibition of 11β-Hydroxylase and 11β-Hydroxysteroid Dehydrogenase 2
por: Thompson, George R, et al.
Publicado: (2019)

Cortisol Release From Adipose Tissue by 11β-Hydroxysteroid Dehydrogenase Type 1 in Humans
por: Stimson, Roland H., et al.
Publicado: (2009)

Organotins Disrupt the 11β-Hydroxysteroid Dehydrogenase Type 2–Dependent Local Inactivation of Glucocorticoids
por: Atanasov, Atanas G., et al.
Publicado: (2005)

Discovery of Adamantyl Heterocyclic Ketones as Potent 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitors
por: Su, Xiangdong, et al.
Publicado: (2011)

Epigenetic Effects of Prenatal Stress on 11β-Hydroxysteroid Dehydrogenase-2 in the Placenta and Fetal Brain
por: Jensen Peña, Catherine, et al.
Publicado: (2012)

Altered Regulation of Type II 11β-hydroxysteroid Dehydrogenase in the Kidney of Rats with Experimental Hypertension
por: Kang, Seong Su, et al.
Publicado: (2007)

Changing glucocorticoid action: 11β-Hydroxysteroid dehydrogenase type 1 in acute and chronic inflammation
por: Chapman, Karen E., et al.
Publicado: (2013)

Adamantyl carboxamides and acetamides as potent human 11β-hydroxysteroid dehydrogenase type 1 inhibitors
por: Su, Xiangdong, et al.
Publicado: (2012)

11β-hydroxysteroid dehydrogenase inhibition as a new potential therapeutic target for alcohol abuse
por: Sanna, P P, et al.
Publicado: (2016)

11β-hydroxysteroid dehydrogenase-1 deficiency alters the gut microbiome response to Western diet
por: Johnson, Jethro S, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_d7gr7k7e04haouge0etjde35vs